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MicroRNA in Development and in the Progression of Cancer

  • Shree Ram Singh
  • Pranela Rameshwar

Table of contents

  1. Front Matter
    Pages i-xiii
  2. The Functions and Mechanisms of MicroRNAs

    1. Front Matter
      Pages 1-1
    2. Abigail F. Olena, James G. Patton
      Pages 3-28
    3. Omozusi Andrews, James G. Patton
      Pages 29-46
    4. Hailiang Hu
      Pages 47-66
  3. MicroRNAs in Stem Cells and Progression of Cancer

    1. Front Matter
      Pages 67-67
    2. Stephanie Rager, Brian Chan, Lyric Forney, Shree Ram Singh
      Pages 69-80
    3. Bernadette Bibber, Garima Sinha, Shyam A. Patel, Pranela Rameshwar, Ryan D. Mohan
      Pages 81-101
    4. George R. Nahas, Bernadette M. Bibber, Pranela Rameshwar
      Pages 103-115
    5. Muthusawamy Thangraju, Ashok Jain
      Pages 117-137
    6. Safak Yalcin, Stephen S. Chung, Christopher Y. Park
      Pages 139-157
    7. Heba Degheidy, Siddha Kasar, Chingiz Underbayev, Yao Yuan, Smruti Mehta, Marilyn Lightfoote et al.
      Pages 159-178
    8. Yiwei Li, Dejuan Kong, Aamir Ahmad, Bin Bao, Fazlul H. Sarkar
      Pages 179-198
    9. Hiromu Suzuki, Eiichiro Yamamoto, Reo Maruyama
      Pages 199-211
    10. Sharanjot Saini, Sumit Arora, Shahana Majid, Hiroshi Hirata, Rajvir Dahiya
      Pages 213-241
    11. Vivek Choudhary, Meg Gullotto, Lisa Sato, Wendy B. Bollag
      Pages 243-264
    12. Nagalakshmi Nadiminty, Ramakumar Tummala, Allen C. Gao
      Pages 265-286
    13. Monika Sangwan, Neetu Dahiya
      Pages 287-302
  4. Role of MicroRNA and Potential Cancer Therapeutics

    1. Front Matter
      Pages 303-303
    2. Daohong Chen, Harikrishna Nakshatri
      Pages 305-326
    3. Krishna C. Vallabhaneni, Patrice Penfornis, J. Griffin Orr, Krishna Chauhan, Radhika Pochampally
      Pages 327-348
    4. Steven J. Greco, Jessian L. Munoz, Pranela Rameshwar
      Pages 349-358
    5. Joseph S. Fernandez-Moure, Jeffrey Van Eps, Bradley K. Weiner, Mauro Ferrari, Ennio Tasciotti
      Pages 359-403
  5. Back Matter
    Pages 405-407

About this book

Introduction

MicroRNAs (miRNAs) are small 22-nucleotides long non-coding RNAs that regulate the gene expression through translational repression and mRNA degradation in varieties of species. miRNAs play regulatory role in several fundamental biological processes from normal development to regulation of stem cells, cancer stem cells and various human diseases including cancer. miRNAs can be used as potential biomarkers for disease diagnosis and have been considered potential therapeutic strategies in cancer treatment.

This is a timely and specialized book providing the current understanding of miRNAs and their potential application in cancer diagnosis, prognosis, and therapeutic strategies in cancer treatment. This book will be a valuable source of information for the scientists in the field of cancer research as well as undergraduate and graduate students who want to pursue their research careers in cancer biology.

Keywords

cancer cancer stem cells gene expression miRNA microRNA

Editors and affiliations

  • Shree Ram Singh
    • 1
  • Pranela Rameshwar
    • 2
  1. 1.National Cancer Institute Mouse Cancer Genetics ProgramFrederickUSA
  2. 2.UMDNJ-NJ Medical SchoolNewarkUSA

Bibliographic information

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