Pluripotency in Domestic Animal Cells

  • Tiziana A.L. Brevini
  • Fulvio Gandolfi

Part of the SpringerBriefs in Stem Cells book series (BRIEFSSTEM)

Table of contents

  1. Front Matter
    Pages i-vii
  2. Tiziana A. L. Brevini, Fulvio Gandolfi
    Pages 1-19
  3. Tiziana A. L. Brevini, Fulvio Gandolfi
    Pages 21-27
  4. Tiziana A. L. Brevini, Fulvio Gandolfi
    Pages 29-42
  5. Back Matter
    Pages 43-46

About this book

Introduction

This addition to the Springer Brief in Stem Cells series focuses on aspects related to the specific mechanisms that ensure and control pluripotency and cell commitment in domestic animal species. This topic is generating rapidly-increasing interest due to the great potential for domestic animal species to be used as intermediate biomedical models, between the mouse and the human. The Brief addresses why we need large animal models for regenerative medicine. It also describes early embryo development with a careful and specific analysis of the regulatory mechanisms driving cleavage, polarization and genome activation in domestic species. How pluripotency is compartmentalized in domestic species as well as the different aspects that make the derivation of stem cells in domestic species very difficult are also addressed.

Keywords

Blastulation Embryogenesis Epiblast Gametogenesis Pluripotency Spindle Formation

Authors and affiliations

  • Tiziana A.L. Brevini
    • 1
  • Fulvio Gandolfi
    • 2
  1. 1.Laboratory of Biomedical Embryology Anatomy and HistologyUniversità degli Studi di Milano UnistemMilanItaly
  2. 2.Laboratory of Biomedical Embryology Anatomy and HistologyUniversità degli Studi di Milano UnistemMilanItaly

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4899-8053-3
  • Copyright Information The Author(s) 2013
  • Publisher Name Springer, New York, NY
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-4899-8052-6
  • Online ISBN 978-1-4899-8053-3
  • Series Print ISSN 2192-8118
  • Series Online ISSN 2192-8126
  • About this book
Industry Sectors
Biotechnology
Pharma