Post-Traumatic Arthritis

Pathogenesis, Diagnosis and Management

  • Steven A. Olson, MD
  • Farshid Guilak, PhD

Table of contents

  1. Front Matter
    Pages i-xx
  2. The Problem of Post-Traumatic Arthritis

    1. Front Matter
      Pages 1-1
    2. Joseph A. Buckwalter, David T. Felson
      Pages 7-15
    3. Jessica C. Rivera, Joseph C. Wenke, James R. Ficke, Anthony E. Johnson
      Pages 17-26
  3. Experimental Models of Joint Injury

    1. Front Matter
      Pages 27-27
    2. Christopher T. Chen, Peter A. Torzilli
      Pages 29-40
    3. Chia-Lung Wu, Dianne Little
      Pages 41-62
    4. Kelly A. Kimmerling, Farshid Guilak
      Pages 63-74
    5. Blaine A. Christiansen, Jasper H. N. Yik, Dominik R. Haudenschild
      Pages 75-85
    6. Bridgette D. Furman, Steven A. Olson
      Pages 87-100
    7. Todd McKinley
      Pages 101-112
    8. Bridgette D. Furman, Kelly A. Kimmerling, Chia-Lung Wu, Dianne Little, Farshid Guilak, Steven A. Olson
      Pages 113-118
  4. Peri-articular Tissues Response to Joint Injury

    1. Front Matter
      Pages 119-119
    2. Yang Wang, Alan J. Grodzinsky
      Pages 121-133
    3. Steven R. Goldring
      Pages 135-147
    4. Muhammad Farooq Rai, Linda J. Sandell
      Pages 149-164
    5. Richard F. Loeser, Cristin M. Ferguson, Martin K. Lotz
      Pages 165-183
    6. Shawn P. Grogan, Martin K. Lotz, Darryl D. D’Lima
      Pages 185-199
    7. Mary B. Goldring
      Pages 201-209
    8. Mitchell C. Coleman, Joseph A. Buckwalter, James A. Martin
      Pages 211-219
    9. Timothy M. Wright, Suzanne A. Maher
      Pages 221-233
  5. Clinical Assessment and Treatment of Patients with Joint Injury

    1. Front Matter
      Pages 235-235
    2. Nathaniel E. Calixto, Aditi Guha, Sharmila Majumdar
      Pages 237-257
    3. Kurt P. Spindler, David N. Wasserstein
      Pages 259-268
    4. Brandi R. Hartley, Craig S. Roberts, Peter V. Giannoudis
      Pages 269-283
    5. Brandi R. Hartley, Craig S. Roberts
      Pages 285-293
    6. Antonia F. Chen, Javad Parvizi
      Pages 295-301
  6. Developing and Future Assessment and Therapies

    1. Front Matter
      Pages 303-303
    2. Yvonne M. Golightly, Samuel B. Adams Jr., Virginia Byers Kraus
      Pages 317-330
    3. Cecilia Pascual-Garrido, Susan Chubinskaya
      Pages 331-342
    4. Farshid Guilak, Brian O. Diekman, Steven A. Olson
      Pages 343-348
    5. Steven A. Olson, Farshid Guilak
      Pages 349-352
  7. Back Matter
    Pages 353-360

About this book


Bringing together the most up-to-date research on post-traumatic arthritis (PTA) and its management, this book is a comprehensive presentation of the current thinking on all aspects of the mechanisms of joint injury and subsequent development of PTA. Divided into thematic sections, it includes discussions of the incidence and burden of PTA, both in society at large and in the military population specifically; the relevant experimental work on PTA, from basic science to animal models; peri-articular tissue responses to of joint injury and potential mechanisms of PTA; the current clinical assessment and treatment of common joint injuries leading to PTA; and emerging technologies and treatments for PTA, including biomarkers and stem cell therapies. Taken together, it will be an invaluable resource for orthopedic surgeons, rheumatologists and other joint injury researchers and clinicians.


Cartilage injury Inflammation Joint injury Oxidative stress Peri-articular tissue damage Post-traumatic arthritis Post-traumatic osteoarthritis Subchondral bone

Editors and affiliations

  • Steven A. Olson, MD
    • 1
  • Farshid Guilak, PhD
    • 2
  1. 1.Professor, Department of Orthopaedic SurgeryDuke University Medical CenterDurhamUSA
  2. 2.Laszlo Ormandy Professor, Department of Orthopedic SurgeryDuke University Medical CenterDurhamUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2015
  • Publisher Name Springer, Boston, MA
  • eBook Packages Medicine
  • Print ISBN 978-1-4899-7605-5
  • Online ISBN 978-1-4899-7606-2
  • Buy this book on publisher's site
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Health & Hospitals