Immunology of HIV Infection

1. Front Matter

   Pages i-xxv

   PDF

2. Basic Mechanisms

   1. Front Matter

      Pages 1-1

      PDF

   2. Genetic Organization of HIV

      • Lee Ratner

      Pages 3-22

   3. T-Cell Epitopes of HIV-1 Envelope Glycoprotein

      • Christopher B. Buck, Robert F. Siliciano

      Pages 23-55

   4. B-Cell Sites in the HIV Glycoproteins

      • Ewa Björling, Erling Norrby

      Pages 57-78

   5. Lymphocyte Adhesion Coreceptors and their Roles in HIV-1 Replication

      • Jeffrey A. Ledbetter

      Pages 79-91

3. Immunopathogenesis

   1. Front Matter

      Pages 93-93

      PDF

   2. HIV in Lymph Node and Thymus

      • Dhavalkumar D. Patel, Laura P. Hale, Barton F. Haynes

      Pages 95-121

   3. Effects of HIV-1 and HIV-1 Envelope Glycoproteins on Signaling Pathways in Human T Lymphocytes

      • Sudhir Gupta

      Pages 123-132

   4. Lymphocyte Apoptosis in HIV Infection

      • Naoki Oyaizu, Savita Pahwa

      Pages 133-159

   5. Biological Activities of HIV-Specific Peptides

      • Stanley A. Schwartz, Madhavan P. N. Nair, Linda B. Ludwig

      Pages 161-179

   6. Phenotype and Function of T Cells in HIV Disease

      • Janis V. Giorgi

      Pages 181-199

   7. Cytotoxic T-Lymphocyte Responses to HIV

      • Brigitte Autran

      Pages 201-228

   8. Type 1 and Type 2 Responses in HIV Infection and Exposure

      • Gene M. Shearer, Mario Clerici

      Pages 229-241

   9. Humoral Immunity to HIV-1:

      • Peter L. Nara

      Pages 243-276

   10. Autoimmunity in HIV

       • Charles S. Via, Arif R. Sarwari

       Pages 277-284

   11. Cytokine Cascades in HIV Infection

       • Guido Poli, Anthony S. Fauci

       Pages 285-301

   12. Macrophage Functions in HIV-1 Infection

       • Sharon M. Wahl, Jan M. Orenstein, Phillip D. Smith

       Pages 303-336

   13. Dendritic Cell Functions in HIV Infection

       • Stella C. Knight

       Pages 337-351

   14. Natural Killer Cells in HIV Infection

       • Benjamin Bonavida, Anahid Jewett

       Pages 353-364

Leading experts provide the only comprehensive book examining all aspects of immune response and immune-based treatments for HIV infection. Contributions, divided into three sections, discuss basic mechanisms, immunopathogenesis of HIV infection, and immune-based therapies. Researchers thoroughly review vaccine-including prospects of T cell vaccine-and gene therapy for HIV infection. Additional topics include organization of HIV genes, the role of co-receptors in signaling of lymphocytes, and biological response modifiers. This reference is designed for basic and clinical researchers, internists, pediatricians, infectious disease specialists, neuropathologists, oncologists, and rheumatologists.

• AIDS
• HIV
• HIV infection
• Thymus
• autoimmunity
• gene therapy
• infection
• infectious
• infectious disease
• interferon
• infectious diseases

`Technical and well documented....a must book for AIDS researchers...highly recommended for all medical libraries.'
AIDS Book Review Journal
`Contains a wealth of information for beginners and experts in the immunology of AIDS...The book challenges its readers to search the evidence for important clues and new leads.'
The New England Journal of Medicine.
`An excellent companion for grant-writung, lecture preparation or fact checking.'
Molecular Medicine Today

• University of California, Irvine, USA

  Sudhir Gupta

Policies and ethics