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  • © 1982

Mechanisms of Cell-Mediated Cytotoxicity

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 146)

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  • ISBN: 978-1-4684-8959-0
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Table of contents (36 chapters)

  1. Front Matter

    Pages i-xiii
  2. Lysis by Cytotoxic T Lymphocytes: Morphological and Physiological Aspects

    1. Front Matter

      Pages 1-2
    2. Cytolytic T Lymphocyte Recognition of Subcellular Antigen

      • Matthew F. Mescher, Steven P. Balk, Steven J. Burakoff, Steven H. Herrmann
      Pages 41-55
    3. Effects of Concanavalin a Pretreatment on Cloned Cytolytic T Cells

      • Katherine A. Wall, Frank W. Fitch
      Pages 101-109
    4. The Role of Calcium in the Lethal Hit of T Lymphocyte-Mediated Cytolysis

      • Eric Martz, Wendy L. Parker, Maurice K. Gately, Constantine D. Tsoukas
      Pages 121-147
  3. Lysis by Non-T Cells and by Complement

    1. Front Matter

      Pages 191-192
    2. ADCC

      1. Lymphocyte Mediated Cytolysis as a Secretory Phenomenon
        • Maryanna P. Henkart, Pierre A. Henkart
        Pages 227-247
      2. Associative Recognition in ADCC
        • Peter Perlmann
        Pages 249-253
      3. Influence of Monovalent Cation Concentrations on Monocyte-Mediated ADCC
        • Stephan Ladisch, Lisa Ulsh, Stephen A. Feig
        Pages 255-264
    3. MØCC

      1. Mechanisms of Macrophage-Mediated Tumor Cytolysis
        • M. E. Key, L. Hoyer, C. Bucana, M. G. Hanna Jr.
        Pages 265-314
      2. Activated Macrophage Mediated Cytotoxicity for Transformed Target Cells
        • John B. Hibbs Jr., Donald L. Granger, James L. Cook, Andrew M. Lewis Jr.
        Pages 315-335

About this book

The First International Workshop on Mechanisms in Cell-Mediated Cytoxicity was held at Carry-Ie-Rouet, France, September 14-16, 1981. The Workshop brought together for the first time leading investiga­ tors in each of the principal areas of cell-mediated cytotoxicity, as well as experts in the area of complement-mediated cytoxicity. Formal research presentations were held to a minimum, the emphasis being on open discussion of current knowledge about mechanisms of cytoxicity in each of the systems under consideration. The major objectives of the Workshop were 1) to compare and integrate what is known about the mechanism(s) of cytoxicity in each system; 2) to determine whether, on the basis of information in hand, it seems likely that the mechanisms of cytotoxicity in the various systems are the same or are unique; and 3) to stimulate thinking about new approaches to elucidating the fundamental mechanisms by which certain cells are able to kill other cells.

Keywords

  • T cell
  • antibody
  • antigen
  • cells
  • cytotoxicity
  • genetics
  • growth factor
  • hand
  • lymphocytes
  • research
  • thinking
  • toxicity

Editors and Affiliations

  • University of California, Los Angeles, USA

    William R. Clark

  • Centre d’lmmunologie, INSERM-CNRS de Marseille-Luminy, Marseille, France

    Pierre Golstein

Bibliographic Information

Buying options

eBook USD 99.00
Price excludes VAT (USA)
  • ISBN: 978-1-4684-8959-0
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book USD 129.00
Price excludes VAT (USA)