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Mechanisms of Cell-Mediated Cytotoxicity

  • Book
  • © 1982
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Overview

Editors:
  1. William R. Clark

    1. University of California, Los Angeles, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Pierre Golstein

    1. Centre d’lmmunologie, INSERM-CNRS de Marseille-Luminy, Marseille, France

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 146)

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Table of contents (36 chapters)

  1. Front Matter

    Pages i-xiii
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  2. Lysis by Cytotoxic T Lymphocytes: Morphological and Physiological Aspects

    1. Front Matter

      Pages 1-2
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    2. Morphological Aspects of Lymphocyte Mediated Cytotoxicity

      • Colin J. Sanderson
      Pages 3-21
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    3. Role of Cell Motility in the Activity of Cytolytic T Lymphocytes

      • J.-E. Ryser, P. Vassalli
      Pages 23-39
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    4. Cytolytic T Lymphocyte Recognition of Subcellular Antigen

      • Matthew F. Mescher, Steven P. Balk, Steven J. Burakoff, Steven H. Herrmann
      Pages 41-55
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    5. T Lymphocyte-Mediated Cytolysis — A Comprehensive Theory I. The Mechanism of CTL-Mediated Cytolysis

      • Gideon Berke, William R. Clark
      Pages 57-68
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    6. T Lymphocyte-Mediated Cytolysis — A Comprehensive Theory II. Lytic vs. Nonlytic Interactions of T Lymphocytes

      • William R. Clark, Gideon Berke
      Pages 69-79
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    7. Studies on the Mechanism of Lectin-Dependent T Cell-Mediated Cytolysis: Use of Lens Culinaris Hemagglutinin A to Define the Role of Lectin

      • William R. Green
      Pages 81-100
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    8. Effects of Concanavalin a Pretreatment on Cloned Cytolytic T Cells

      • Katherine A. Wall, Frank W. Fitch
      Pages 101-109
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    9. Sequential Analysis of T Cell-Mediated Cytolysis: A Brief Reminder of Some Possibly Informative Markers at the Recognition and Lethal Hit Stages

      • Pierre Golstein
      Pages 111-119
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    10. The Role of Calcium in the Lethal Hit of T Lymphocyte-Mediated Cytolysis

      • Eric Martz, Wendy L. Parker, Maurice K. Gately, Constantine D. Tsoukas
      Pages 121-147
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    11. Direct Analysis of Individual Killer T Cells: Susceptibility of Target Cells to Lysis and Secretion of Hydrolytic Enzymes by CTL

      • D. Zagury
      Pages 149-169
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    12. The Differences in Receptor Cross Reactivity and Clonal Structure Between Cytotoxic T Lymphocytes, Specific Suppressor T Cells and Memory T Cells Immune to Antigens of the H-2 Complex

      • B. D. Brondz, I. F. Abronina, Z. K. Blandova, A. V. Karaulov, A. A. Pimenov
      Pages 171-189
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  3. Lysis by Non-T Cells and by Complement

    1. Front Matter

      Pages 191-192
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    3. ADCC

      1. Lymphocyte Mediated Cytolysis as a Secretory Phenomenon
        • Maryanna P. Henkart, Pierre A. Henkart
        Pages 227-247
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      2. Associative Recognition in ADCC
        • Peter Perlmann
        Pages 249-253
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      3. Influence of Monovalent Cation Concentrations on Monocyte-Mediated ADCC
        • Stephan Ladisch, Lisa Ulsh, Stephen A. Feig
        Pages 255-264
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    4. MØCC

      1. Mechanisms of Macrophage-Mediated Tumor Cytolysis
        • M. E. Key, L. Hoyer, C. Bucana, M. G. Hanna Jr.
        Pages 265-314
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      2. Activated Macrophage Mediated Cytotoxicity for Transformed Target Cells
        • John B. Hibbs Jr., Donald L. Granger, James L. Cook, Andrew M. Lewis Jr.
        Pages 315-335
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Keywords

About this book

The First International Workshop on Mechanisms in Cell-Mediated Cytoxicity was held at Carry-Ie-Rouet, France, September 14-16, 1981. The Workshop brought together for the first time leading investiga­ tors in each of the principal areas of cell-mediated cytotoxicity, as well as experts in the area of complement-mediated cytoxicity. Formal research presentations were held to a minimum, the emphasis being on open discussion of current knowledge about mechanisms of cytoxicity in each of the systems under consideration. The major objectives of the Workshop were 1) to compare and integrate what is known about the mechanism(s) of cytoxicity in each system; 2) to determine whether, on the basis of information in hand, it seems likely that the mechanisms of cytotoxicity in the various systems are the same or are unique; and 3) to stimulate thinking about new approaches to elucidating the fundamental mechanisms by which certain cells are able to kill other cells.

Editors and Affiliations

  • University of California, Los Angeles, USA

    William R. Clark

  • Centre d’lmmunologie, INSERM-CNRS de Marseille-Luminy, Marseille, France

    Pierre Golstein

Bibliographic Information

  • Book Title: Mechanisms of Cell-Mediated Cytotoxicity

  • Editors: William R. Clark, Pierre Golstein

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4684-8959-0

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1982

  • Softcover ISBN: 978-1-4684-8961-3Published: 26 November 2012

  • eBook ISBN: 978-1-4684-8959-0Published: 11 November 2013

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XIII, 597

  • Topics: Immunology

  • Industry Sectors: Biotechnology, Consumer Packaged Goods, Health & Hospitals, Pharma

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