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  • © 1983

Beneficial Effects of Endotoxins

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Table of contents (28 chapters)

  1. Front Matter

    Pages i-xiii
  2. Effect of LPS on Carbohydrate and Lipid Metabolism

    • Judy A. Spitzer, John J. Spitzer
    Pages 57-74
  3. Effect of LPS On the Clotting System

    • Alexander M. Abdelnoor
    Pages 75-90
  4. Immunogenicity of Endotoxin

    • Erwin Neter
    Pages 91-109
  5. Protection against Gram-Negative Bacteremia with Antiserum to Endotoxins

    • Abraham I. Braude, Elizabeth J. Ziegler
    Pages 111-125
  6. The Radioprotective Effect of Bacterial Endotoxin

    • Ulrich H. Behling
    Pages 127-148
  7. Induction of Endotoxin Tolerance

    • Sheldon Edward Greisman
    Pages 149-178
  8. In Vitro Adjuvant Effect of Endotoxin

    • Masayasu Nakano, Takehiko Uchiyama
    Pages 255-272
  9. Stimulation of Immunomodulatory Factors by Bacterial Endotoxins and Nontoxic Polysaccharides

    • Herman Friedman, Steven Specter, R. Christopher Butler
    Pages 273-282
  10. Interleukin 1

    • Lawrence B. Lachman
    Pages 283-305
  11. Immunomodulatory Effects of Endotoxin

    • Diane M. Jacobs
    Pages 307-325
  12. Lipopolysaccharide Regulation of the Immune Response

    • Katherine A. Gollahon, Suzanne M. Michalek, Michael J. Wannemuehler, Jerry R. McGhee
    Pages 327-353
  13. The Role of Humoral Factors in Endotoxin-Induced Reactions

    • L. Joe Berry, Jeanne E. Gaska
    Pages 355-380
  14. Induction of Interferon by Endotoxin

    • Monto Ho
    Pages 381-395

About this book

The study of endotoxins has undergone cycles of enthusiastic research followed by neglect and revival again due to newly described biological effects attributed to endotoxins. It is almost a generally applicable rule that both extremes in such fluctuations in the popularity of certain re­ search fields are unjustified. It is obvious that exaggerated expectations will lead to disappointments, and complete neglect of a once-exciting field is to be followed by renewed attention, if the scientific basis of earlier interest was solid and remained so throughout. The healing ef­ fect of fever was praised as nature's blessed cure, until it was discov­ ered that it is caused by bacteria. When it became evident that by careful application one can arrive at therapeutic doses without intro­ ducing shock and hypotension, the era of fever therapy began. During this time, indiscriminate use of pyrogens was so widespread that the high expectations had to be followed by disillusionment. Since then, in­ terest in endotoxins experienced a few more oscillations, with varying wavelengths and amplitudes, the latest being triggered by the mitotic effect of endotoxin. This led to justified excitement among researchers who study the activation of the cells of the lymphatic system and the consequences thereof, including the release of important mediator mol­ ecules. Fever therapy is passe, but the healing that often followed the ap­ plication of endotoxins remains a well-documented fact.

Keywords

  • Colon
  • Lipid
  • Polysaccharid
  • bacteria
  • immunotherapy
  • interferon
  • kidney
  • lead
  • lipide
  • metabolism
  • plant
  • protein
  • research
  • resistance
  • transplantation

Editors and Affiliations

  • Center for Oral Health Research, School of Dental Medicine, University of Pennsylvania, Philadelphia, USA

    Alois Nowotny

Bibliographic Information

Buying options

eBook USD 59.99
Price excludes VAT (USA)
  • ISBN: 978-1-4684-4364-6
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book USD 79.99
Price excludes VAT (USA)