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Table of contents (10 chapters)
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Front Matter
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Concepts and Mechanisms
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Front Matter
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Back Matter
About this book
Modification of existing therapies based on the pursuit of leads arising from mechanistic studies is also being applied clinically on a wide scale. Greater understanding should follow from the studies of reversal of the multidrug resistant phenotype, on the use of hydroxyurea to reverse resistance mediated by extrachromosomal DNA, and on various aspects of the fluoropyrimidine pathways.
Successful applications of chemotherapy to the treatment of specific diseases include the growing applications of systemic therapy using various skin malignancies. In prostate cancer, estramustine phosphate will likely play an expanding role. Taxanes are restructuring treatment regimens in breast cancer, and high-dose strategies are described with peripheral blood progenitor autografting in the treatment of ovarian and breast cancers.
Editors and Affiliations
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University of Southern California Cancer Center, USA
F. M. Muggia
Bibliographic Information
Book Title: Concepts, Mechanisms, and New Targets for Chemotherapy
Editors: F. M. Muggia
Series Title: Cancer Treatment and Research
DOI: https://doi.org/10.1007/978-1-4615-2007-8
Publisher: Springer New York, NY
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eBook Packages: Springer Book Archive
Copyright Information: Springer Science+Business Media New York 1995
Hardcover ISBN: 978-0-7923-3525-2Published: 31 December 1995
Softcover ISBN: 978-1-4613-5829-9Published: 22 December 2012
eBook ISBN: 978-1-4615-2007-8Published: 06 December 2012
Series ISSN: 0927-3042
Series E-ISSN: 2509-8497
Edition Number: 1
Number of Pages: X, 237
Topics: Oncology, Cancer Research, Medicine/Public Health, general
Industry Sectors: Biotechnology, Health & Hospitals, Pharma