Cardiovascular Genomics: New Pathophysiological Concepts

Proceedings of the 2001 European Science Foundation Workshop in Maastricht

  • Pieter A. Doevendans
  • Stefan Kääb

Part of the Developments in Cardiovascular Medicine book series (DICM, volume 242)

Table of contents

  1. Front Matter
    Pages i-xix
  2. Genomics and Clinical Cardiology: Hype or Hope?

  3. Gene expression analysis

    1. Front Matter
      Pages 5-5
    2. B. C. Rossier, D. Firsov
      Pages 7-19
    3. C. Michiels, D. Mottet, E. Delaive, M. Dieu, J-F. Dierick, J. Remacle
      Pages 21-28
  4. Genomics and pathophysiology of atherosclerosis

    1. Front Matter
      Pages 41-41
    2. A. J. G. Horrevoets, R. J. Dekker, R. D. Fontijn, S. van Soest, H. Pannekoek
      Pages 43-52
  5. Genomics in hypertension

    1. Front Matter
      Pages 53-53
    2. X. Jeunemaitre, S. Disse-Nicodème, A. Gimenez-Roqueplo, P. Corvol
      Pages 55-63
    3. J. P. Fennell, M. J. Brosnan, A. J. Frater, A. H. Baker, A. F. Dominiczak
      Pages 65-75
    4. G. Lembo
      Pages 77-81
    5. C. Zaragoza, S. Lamas
      Pages 83-94
  6. Genomics in cardiac hypertrophy and failure

    1. Front Matter
      Pages 95-95
    2. B. J. C. van den Bosch, P. A. Doevendans, D. J. Lips, J. M. W. Geurts, H. J. M. Smeets
      Pages 97-105
    3. G. Esposito, A. Rapacciuolo, S. V. Naga Prasad, H. A. Rockman
      Pages 107-114
    4. O. F. Bueno, E. van Rooij, D. J. Lips, P. A. Doevendans, L. J. De Windt
      Pages 131-156
  7. Molecular remodelling in arrhythmias

    1. Front Matter
      Pages 157-157
    2. M. Stengl, P. G. A. Volders, M. A. Vos
      Pages 167-185
    3. S. Kääb, M. Näbauer, A. Pfeufer
      Pages 187-198
    4. B. J. J. M. Brundel, R. H. Henning, H. H. Kampinga, I. C. Van Gelder, H. J. G. M. Crijns
      Pages 199-212
    5. U. Ravens, E. Wettwer, T. Christ, D. Dobrev
      Pages 213-222
  8. Towards cellular transplantion

    1. Front Matter
      Pages 223-223
    2. A. A. F. De Vries
      Pages 225-230
    3. C. Mummery, D. Ward, C. E. van den Brink, S. D. Bird, P. A. Doevendans, D. J. Lips et al.
      Pages 231-243
    4. P. Menasché
      Pages 257-264
  9. Back Matter
    Pages 273-275

About this book


Four years ago-in December 1997-the first European Science Foundation Workshop on Cardiovascular Specific Gene Expression was held in Maastricht. It was hardly possible to imagine the progress in the field in those four years. In 1997, gene expression was still an art focused on individual genes; in 200 I, many labs have access to micro-array facilities to determine the expression of thousands of genes simultaneously. In 1997, gene expression was an area of fundamental research in basis molecular biology laboratories; in 200 I, clinical cardiovascular research has incorporated gene expression approaches. In 1997, the interpretation of a gene expression experiment was usually straightforward; in 200 I, advanced bioinformatics tools are needed to approach the extreme complexities of genetic control of cell and tissue function. The second symposium in this series is focused on Cardiovascular Genomics. New Pathophysiological Concepts. The organizing committee chose to invite a group of renown scientists and young investigators around four topics of eminent importance in cardiovascular research. These topics reflect the major present-day clinical cardiovascular problems: atherosclerosis, hypertension, arrhythmias and heart failure. In addition to these four disease-driven topics, the workshop has sessions on gene expression methodologies and cellular transplant approaches to cardiovascular disease.


Microarray cardiovascular gene expression gene therapy genes genetics hypertension molecular mechanisms

Editors and affiliations

  • Pieter A. Doevendans
    • 1
  • Stefan Kääb
    • 2
  1. 1.Academic Hospital MaastrichtMaastrichtGermany
  2. 2.Klinikum GrosshadernMunichGermany

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2002
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-5347-8
  • Online ISBN 978-1-4615-1005-5
  • Series Print ISSN 0166-9842
  • Buy this book on publisher's site
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