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Non-Myeloablative Allogeneic Transplantation

  • Book
  • © 2002

Overview

Editors:
  1. Asad Bashey

    1. Blood and Marrow Transplantation Division, University of California, San Diego, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Edward D. Ball

    1. Blood and Marrow Transplantation Division, University of California, San Diego, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Cancer Treatment and Research (CTAR, volume 110)

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Table of contents (9 chapters)

  1. Front Matter

    Pages i-x
    Download chapter PDF

  2. Development of Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

    • Januario E. Castro, Edward D. Ball
    Pages 1-37

  3. Immunosuppression with Limited Toxicity: The Characteristics of Nucleoside Analogs and Anti-Lymphocyte Antibodies Used in Nonmyeloablative Hematopoietic Cell Transplantation

    • Asad Bashey
    Pages 39-49

  4. Mobilization of Allogeneic Peripheral Blood Progenitor Cells

    • Ping Law, Thomas A. Lane
    Pages 51-77

  5. Non-Myeloblative Induction of Mixed Hematopoietic Chimerism: Application to Transplantation Tolerance and Hematologic Malignancies in Experimental and Clinical Studies

    • Megan Sykes, Thomas R. Spitzer
    Pages 79-99

  6. Combined Use of Auto-Grafting and Non-Myeloablative Allografting for the Treatment of Hematologic Malignancies and Metastatic Breast Cancer

    • Angelo M. Carella, Germana Beltrami, Enrica Lerma, Marina Cavaliere, Maria T. Corsetti
    Pages 101-112

  7. Non-Myeloablative Hematopoietic Stem Cell Transplantation (NST) in the Treatment of Human Malignancies: From Animal Models to Clinical Practice

    • Avichai Shimoni, Arnon Nagler
    Pages 113-136

  8. Non-Myeloablative Allogeneic Hematopoietic Transplantation and Induction of Graft-Versus-Malignancy

    • Issa Khouri, Sergio Giralt, Richard Champlin
    Pages 137-147

  9. Outpatient Allografting in Hematologic Malignancies and Nonmalignant Disorders — Applying Lessons Learned in the Canine Model to Humans

    • Michael Maris, Rainer Storb
    Pages 149-175

  10. Non-Myeloablative Transplants for Congenital Diseases

    • Jody Donahue, Ewa Carrier
    Pages 177-211

  11. Back Matter

    Pages 213-216
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Keywords

About this book

Non-myeloablative allogeneic stem cell transplantation (also known as mini-transplantation or reduced-intensity conditioning transplantation) is a major advance in the field of hematopoietic transplantation within the last 5 years. This approach uses non-cytotoxic or reduced-intensity cytotoxic therapy to prepare patients for allografting of hematopoietic stem cells and lymphocytes. It has the potential to deliver the potent anti-tumor immunotherapy and bone marrow replacement capacity of allogeneic stem cell transplantation to patients with reduced treatment-related morbidity and mortality. It may also enable allogeneic transplantation in patients who would be considered ineligible for conventional transplants because of co-morbidity or advanced age. However, this approach may necessitate more careful monitoring of post-transplant chimerism and malignant disease-status than is usual with conventional allografting. There is also controversy regarding the best preparative regimen and graft-versus-host disease prophylaxis to use.

Editors and Affiliations

  • Blood and Marrow Transplantation Division, University of California, San Diego, USA

    Asad Bashey, Edward D. Ball

Bibliographic Information

  • Book Title: Non-Myeloablative Allogeneic Transplantation

  • Editors: Asad Bashey, Edward D. Ball

  • Series Title: Cancer Treatment and Research

  • DOI: https://doi.org/10.1007/978-1-4615-0919-6

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 2002

  • Hardcover ISBN: 978-0-7923-7646-0Published: 28 February 2002

  • Softcover ISBN: 978-1-4613-5304-1Published: 30 October 2012

  • eBook ISBN: 978-1-4615-0919-6Published: 06 December 2012

  • Series ISSN: 0927-3042

  • Series E-ISSN: 2509-8497

  • Edition Number: 1

  • Number of Pages: X, 216

  • Topics: Oncology, Transplant Surgery

  • Industry Sectors: Biotechnology, Health & Hospitals, Pharma

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