Testosterone: From Basic Research to Clinical Applications

  • Lee B. Smith
  • Rod T. Mitchell
  • Iain J. McEwan

Part of the SpringerBriefs in Reproductive Biology book series (BRIEFSREPROBIO)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Lee B. Smith, Iain J. McEwan
    Pages 1-7
  3. Lee B. Smith, Iain J. McEwan
    Pages 9-16
  4. Lee B. Smith, Iain J. McEwan
    Pages 17-27
  5. Lee B. Smith, Iain J. McEwan
    Pages 29-35
  6. Lee B. Smith, Iain J. McEwan
    Pages 37-57
  7. Lee B. Smith, Iain J. McEwan
    Pages 59-69
  8. Back Matter
    Pages 71-73

About this book


This volume provides a brief résumé of the history of testosterone research, from the early pioneers through to the most recent advances in the field. We discover how steroid hormones were first identified and how testosterone was shown to be essential for male development. Moving forward we explore how and where testosterone is produced, and how the body controls testosterone production. We then investigate the impact testosterone has on different body systems both during their development and function, and how perturbation of testosterone action is associated with disease. We complete our story with an exploration of the emerging roles of testosterone in clinical therapy, and the future potential for manipulation of the testosterone signaling system for human health benefit.


Androgen Receptor Endocrinology Fertility Masculinization Testis Function Testosterone

Authors and affiliations

  • Lee B. Smith
    • 1
  • Rod T. Mitchell
    • 2
  • Iain J. McEwan
    • 3
  1. 1.MRC Centre for Reproductive Health The Queen’s Medical Research CouncilUniversity of EdinburghEdinburghUnited Kingdom
  2. 2.MRC Center for Reproductive HealthQueens Medical Research Institute University of EdinburghEdinburghUnited Kingdom
  3. 3.School of Medical SciencesUniversity of Aberdeen Inst. Medical SciencesAberdeenUnited Kingdom

Bibliographic information

  • DOI
  • Copyright Information The Author(s) 2013
  • Publisher Name Springer, New York, NY
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-4614-8977-1
  • Online ISBN 978-1-4614-8978-8
  • Series Print ISSN 2194-4253
  • Series Online ISSN 2194-4261
  • Buy this book on publisher's site
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