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Molecular Genetics of Axial Patterning, Growth and Disease in the Drosophila Eye

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  • © 2013

Overview

  • Most updated title in the past ten years to cover this topic

  • Reviews all molecular genetic aspects of axial patterning in the drosophila eye

  • Reviews the research and relates it to how it can transform our understanding of human diseases like cancer?

  • Includes supplementary material: sn.pub/extras

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Table of contents (12 chapters)

Keywords

About this book

Undoubtedly, Drosophila melanogaster, fruit fly, has proved to be one of the most popular invertebrate model organisms, and the work horse for modern day biologists. Drosophila, a highly versatile model with a genetic legacy of more than a century, provides powerful genetic, cellular, biochemical and molecular biology tools to address many questions extending from basic biology to human diseases.  One of the most important questions in biology focuses on how does a multi-cellular organism develop from a single-celled embryo. The discovery of the genes responsible for pattern formation has helped refine this question, and led to other questions, such as the role of various genetics and cell biological pathways in regulating the crucial process of pattern formation and growth during organogenesis.  Drosophila eye model has been extensively used to study molecular genetic mechanisms involved in patterning and growth. Since the genetic machinery involved in the Drosophila eye is similar to humans, it has been used to model human diseases and homology to eyes in other taxa. This book will discuss molecular genetic mechanisms of pattern formation, mutations in axial patterning, Genetic regulation of growth in Drosophila eye, and more. There have been no titles in the past ten years covering this topic, thus an update is urgently needed.​

Editors and Affiliations

  • Department of Biology, University of Dayton, Dayton, USA

    Amit Singh

  • Department of Biology Office: SC303C, University of Dayton, Dayton, USA

    Madhuri Kango-Singh

Bibliographic Information

  • Book Title: Molecular Genetics of Axial Patterning, Growth and Disease in the Drosophila Eye

  • Editors: Amit Singh, Madhuri Kango-Singh

  • DOI: https://doi.org/10.1007/978-1-4614-8232-1

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media New York 2013

  • Softcover ISBN: 978-1-4939-5303-5Published: 23 August 2016

  • eBook ISBN: 978-1-4614-8232-1Published: 14 September 2013

  • Edition Number: 1

  • Number of Pages: XIV, 368

  • Number of Illustrations: 5 b/w illustrations, 63 illustrations in colour

  • Topics: Human Genetics, Animal Models, Biomedicine general

  • Industry Sectors: Biotechnology, Pharma

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