• Gabor M. Rubanyi

Part of the Clinical Physiology Series book series (CLINPHY)

Table of contents

  1. Front Matter
    Pages i-1
  2. Paul M. Vanhoutte, Thomas Gräser, Thomas F. Lüscher
    Pages 3-16
  3. Penny E. Phillips, Christina Cade, Lynne H. Parker Botelho, Gabor M. Rubanyi
    Pages 31-40
  4. Hitoshi Miyazaki, Motohiro Kondoh, Yasushi Masuda, Hirotoshi Watanabe, Kazuo Murakami
    Pages 58-71
  5. Lynne H. Parker Botelho, Christina Cade, Penny E. Phillips, Gabor M. Rubanyi
    Pages 72-102
  6. Tommy A. Brock, N. Raju Danthuluri
    Pages 103-124
  7. Thomas F. Lüscher, Chantal Boulanger, Zhihong Yang, Yasuaki Dohi
    Pages 125-136
  8. Victor J. Dzau, Richard E. Pratt, John P. Cooke
    Pages 137-143
  9. Winifred G. Nayler, Xin Hua Gu
    Pages 144-157
  10. Andrew J. King, Barry M. Brenner
    Pages 158-178
  11. Regina M. Botting, John R. Vane
    Pages 238-257
  12. Gabor M. Rubanyi, John T. Shepherd
    Pages 258-271
  13. Back Matter
    Pages 273-277

About this book


Merely three years after the discovery of endothelin, a large amount of information has been generated about the molecular biology, biosynthesis, biological actions and potential physiological and pathological importance of this unique peptide and its isoforms. This first book on endothelins summarizes the early events which lead to the discovery of endothelin, the progress made in understanding the peptide's physiological role, and the current state-of-the-art in contemporary endothelin research. The book also discusses the potential significance of endothelins in health and disease, covers the potential role of the peptides in the integrated control of the cardiovascular system, and outlines future research directions. This comprehensive monograph is an indispensable reference for basic scientists and clinicians.


Endothelin biology cardiovascular cardiovascular system central nervous system endothelium heart heart failure hypertension myocardial infarction physiology smooth muscle tissue vascular disease

Editors and affiliations

  • Gabor M. Rubanyi
    • 1
  1. 1.Institute of Pharmacology, Research CenterSchering AGBerlinGermany

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