Physiology of Inflammation

  • Klaus Ley

Part of the Methods in Physiology Series book series (METHPHYS)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Klaus Ley
    Pages 1-10
  3. Douglas E. Wright, Irving L. Weissman
    Pages 11-51
  4. Joel Linden
    Pages 52-64
  5. Virginia H. Huxley, Rolando E. Rumbaut
    Pages 65-79
  6. Francis W. Luscinskas
    Pages 80-89
  7. Andrew D. Luster, James MacLean
    Pages 90-110
  8. Per Hedqvist, Lennart Lindbom
    Pages 111-130
  9. B. Paul Morgan
    Pages 131-145
  10. Katharina Wenzel-Seifert, Roland Seifert
    Pages 146-188
  11. Bernard M. Babior, Carolyn R. Hoyal, Robert I. Lehrer, Tomas Ganz
    Pages 189-203
  12. Michael B. Lawrence
    Pages 204-221
  13. Geoffrey S. Kansas
    Pages 222-241
  14. Michael L. Dustin
    Pages 242-262
  15. Sharon J. Hyduk, Myron I. Cybulsky
    Pages 263-284
  16. Christopher D. Buckley, David H. Adams, David L. Simmons
    Pages 285-302
  17. Brian Stein, Yeesim Khew-Goodall, Mathew Vadas
    Pages 338-380
  18. Daniel C. Bullard
    Pages 381-401
  19. Dario C. Altieri
    Pages 402-422
  20. Tom Van Der Poll, Marcel Levi, Sander J. H. Van Deventer
    Pages 423-436
  21. Norman R. Harris, D. Neil Granger
    Pages 437-446
  22. Allan M. Lefer, Rosario Scalia
    Pages 447-472
  23. Brent Johnston, Paul Kubes
    Pages 473-495
  24. John Savill, Chris Haslett
    Pages 496-525
  25. Back Matter
    Pages 527-546

About this book


This book covers the physiological processes relevant to inflammation. Although the problem is addressed from a vascular perspective, pathological aspects are also considered. The book centers on the recruitment of leukocytes to sites of injury and infection, their function in the tissue, and the eventual resolution of inflammation. It starts with the formation of leukocytes and the physiology of their transport to the sites of inflammation, considers endothelial activation, and covers all kinds of leukocyte activators including chemokines. Signal transduction pathways for chemoattractants and the activation of neutrophil functions are discussed. Several chapters review the various adhesion molecules and pertinent methods to study their function, including flow chambers, knockout mice, measurement of soluble adhesion molecules and intravital microscopy. The book is aimed at medical residents, graduate students, postdoctoral fellows, and physicians and scientists in physiology, pharmacology, biomedical engineering, pathology, immunology, infectious disease and related disciplines. It is intended to serve as an advanced textbook or reference for studying the physiology of inflammation.


Inflammation Vascular Perspective activation cell cytokine immunology leukocytes microscopy migration physiology regulation tissue

Editors and affiliations

  • Klaus Ley
    • 1
  1. 1.Department of Biomedical EngineeringUniversity of Virginia School of MedicineCharlottesvilleUSA

Bibliographic information