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Stem Cells and Prostate Cancer

  • Book
  • © 2013

Overview

Editors:
  1. Scott D. Cramer

    1. Anschutz Medical Campus, University of Colorado, Aurora, USA

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  • Explores the role of the stem cell in prostate cancer research

  • Discusses the role of the prostate cancer microenvironment in the regulation of the stem cell niche

  • Examines the use of stem cells to model prostate cancer genetics

  • Includes supplementary material: sn.pub/extras

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Table of contents (9 chapters)

  1. Front Matter

    Pages i-vii
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  2. Prostate Stem Cells, Hormones, and Development

    • Gail S. Prins, Wen-Yang Hu
    Pages 1-20

  3. Isolation and Characterization of Prostate Stem Cells

    • Andrew S. Goldstein, Owen N. Witte
    Pages 21-36

  4. Prostate Cancer Stem Cells: A Brief Review

    • Xin Chen, Dean G. Tang
    Pages 37-49

  5. Cancer Stem Cells Provide New Insights into the Therapeutic Responses of Human Prostate Cancer

    • Fiona M. Frame, Norman J. Maitland
    Pages 51-75

  6. Genetic and Signaling Pathway Regulations of Tumor-Initiating Cells of the Prostate

    • David J. Mulholland, Hong Wu
    Pages 77-89

  7. The Prostate Stem Cell Niche

    • David Moscatelli, E. Lynette Wilson
    Pages 91-109

  8. Tumour Stroma Control of Human Prostate Cancer Stem Cells

    • Gail P. Risbridger, Renea A. Taylor
    Pages 111-125

  9. Targeting the Prostate Stem Cell for Chemoprevention

    • Molishree U. Joshi, Courtney K. von Bergen, Scott D. Cramer
    Pages 127-148

  10. Stem Cell Models for Functional Validation of Prostate Cancer Genes

    • Lindsey Ulkus, Min Wu, Scott D. Cramer
    Pages 149-173

  11. Back Matter

    Pages 175-182
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Keywords

About this book

​​​​Recent evidence demonstrates that normal prostate tissue contains stem cells.  There is also accumulating evidence that prostate cancer contains a population of cells with stem cell-like characteristics referred to as cancer stem cells, or tumor initiating cells.  Both the normal prostate stem cell and cancer stem cell populations have important implications for the generation, therapeutic targeting, and prevention of prostate cancer.  The purpose of this book is to explore the role of stem cells in prostate cancer, which is becoming an increasingly hot trend in cancer research. ​

Editors and Affiliations

  • Anschutz Medical Campus, University of Colorado, Aurora, USA

    Scott D. Cramer

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