Epigenetic Approaches to Allergy Research

1. Front Matter

   Pages i-viii

   PDF

2. Introduction

   • Marién Pascual, Sergio Roa

   Pages 1-2

3. Immune System and Atopic Disorders

   • Marién Pascual, Sergio Roa

   Pages 3-21

4. Epigenetics

   • Marién Pascual, Sergio Roa

   Pages 23-50

5. Epigenetics, Environment, and Allergic Diseases

   • Marién Pascual, Sergio Roa

   Pages 51-62

6. Conclusions and Future Perspectives

   • Marién Pascual, Sergio Roa

   Pages 63-64

In recent years, epigenetic approaches to existing scientific problems have offered many new and exciting perspectives. This book focuses on epigenetic approaches to study asthma and allergy research. The authors briefly review cellular factors, immune signaling, and inflammatory pathways in allergy and asthma, as well as genetic influences in the pathogenesis of atopic disorders. Diseases that have been clearly linked to an epigenetic dysregulation will be discussed, as well as the role of epigenetics in the origin of complex diseases. The authors will examine the impact of environment factors in the predisposition to atopic disorders, and they will also describe the major unanswered questions and future perspectives of an exciting new field that studies allergic diseases from the epigenetic point of view.       

• Asthma
• Atopic disorders
• Epigenetics
• gene expression

• Center for Applied Medical Research (CIM, Oncology Division, University of Navarra, Pamplona, Spain

  Marién Pascual

• Center for Applied Medical Research, University of Navarra, Pamplona, Spain

  Sergio Roa

Policies and ethics