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  • Book
  • © 2011

Controlled Release in Oral Drug Delivery

  • Each chapter covers historical overview, candidate drugs, factors influencing design and development, formulation and manufacturing and delivery system design
  • Provides focus on specific topics, complementing other books in the initial CRS series
  • Each chapter sets the context for the inventions described and describe the latitude that the inventions allow
  • Includes supplementary material: sn.pub/extras

Part of the book series: Advances in Delivery Science and Technology (ADST)

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-xiii
  2. Animal Model Systems Suitable for Controlled Release Modeling

    • Steven C. Sutton, Philip L. Smith
    Pages 71-90
  3. Oral Controlled Delivery Mechanisms and Technologies

    • Hossein Omidian, Shahin Fesharaki, Kinam Park
    Pages 109-129
  4. Drug–Polymer Matrices for Extended Release

    • Sandip B. Tiwari, James DiNunzio, Ali Rajabi-Siahboomi
    Pages 131-159
  5. Ion-Exchange Approaches to Controlling Drug Release

    • Der-Yang Lee, Timothy Kutch, Rick S. Chan
    Pages 161-177
  6. Pulsatile Delivery for Controlling Drug Release

    • Sumalee Thitinan, Jason T. McConville
    Pages 179-201
  7. Ordered Mesoporous Silica for the Delivery of Poorly Soluble Drugs

    • Michiel Van Speybroeck, Randy Mellaerts, Johan Adriaan Martens, Pieter Annaert, Guy Van den Mooter, Patrick Augustijns
    Pages 203-219
  8. Extrudable Technologies for Controlling Drug Release and Absorption

    • Daniel Bar-Shalom, Matthew Roberts, James L. Ford
    Pages 239-256
  9. Coated Multiparticulates for Controlling Drug Release

    • Brigitte Skalsky, Sven Stegemann
    Pages 257-276
  10. Lipids in Oral Controlled Release Drug Delivery

    • Ben J. Boyd, Tri-Hung Nguyen, Anette Müllertz
    Pages 299-327
  11. Buccal Drug Delivery

    • Michael A. Repka, Li-lan Chen, Rick S. Chan
    Pages 329-359
  12. Controlling Release by Gastroretention

    • Mark D. Coffin, Matthew D. Burke
    Pages 361-383
  13. Drug Delivery to the Colon

    • Abdul W. Basit, Emma L. McConnell
    Pages 385-399
  14. Back Matter

    Pages 401-412

About this book

Controlled Release in Oral Drug Delivery provides focus on specific topics, complementing other books in the initial CRS series. Each chapter sets the context for the inventions described and describe the latitude that the inventions allow. In order to provide some similar look to each chapter, the coverage includes the historical overview, candidate drugs, factors influencing design and development, formulation and manufacturing and delivery system design. This volume was written along three main sections: the relevant anatomy and physiology, a discussion on candidates for oral drug delivery and the major three groups of controlled release systems: diffusion control (swelling and inert matrices); environmental control (pH sensitive coatings, time control, enzymatic control, pressure control) and finally lipidic systems.

Editors and Affiliations

  • The John Arbuthnott Building, Strathclyde Institute of Pharmacy and Bi, Glasgow, United Kingdom

    Clive G. Wilson

  • Devon, USA

    Patrick J. Crowley

About the editors

Clive Wilson is the J. P. Todd Professor of Pharmaceutics at Strathclyde University in Glasgow, Scotland and the current president of the European Union Federation for Pharmaceutical Sciences. He is the Chief Scientist of Bio-Images Research Group, a Phase II imaging specialist clinical unit in Glasgow Royal Infirmary.

Major areas of research have been the study of the behaviour of drug formulations in man.  With colleagues at Nottingham, he pioneered applications of scintigraphy in the study of physiological and patho-physiological effects of transit on drug absorption and began the investigations into regional drug absorption in man.  This was later applied to the design and optimisation of oral dosage forms, in silico modelling of formulations in man and  studies on IVIVR. He has published more than 150 papers, six books and over 130 reviews and book chapters. He was made a fellow of the Controlled Release Society in June 2010 and a Fellow of the Academy of Pharmaceutical Sciences in September 2010.

 

Patrick Crowley has over 40 years’ experience in dosage form development in the pharmaceutical industry, in both the UK and USA.  He has played key roles in the development of 16 commercial products, including fermentation products, semi synthetics, synthetic structures and a biopharmaceutical product and holds several formulation-related Patents. His interests and publications include drug and product stability, enhancing performance by dosage form design and the application of Quality by Design principles and practices in dosage form development, manufacture and control.

Bibliographic Information

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access