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  • Conference proceedings
  • © 1984

Platinum Coordination Complexes in Cancer Chemotherapy

Proceedings of the Fourth International Symposium on Platinum Coordination Complexes in Cancer Chemotherapy convened in Burlington, Vermont by the Vermont Regional Cancer Center and the Norris Cotton Cancer Center, June 22–24, 1983

Editors:

  1. Miles P. Hacker

    1. Vermont Regional Cancer Center and Department of Pharmacology, University of Vermont, Burlington, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Evan B. Douple
    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  3. Irwin H. Krakoff
    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Developments in Oncology (DION, volume 17)

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Table of contents (28 papers)

  1. Front Matter

    Pages i-xiv
    PDF

  2. Nomenclature

    1. Front Matter

      Pages 1-1
      PDF

  3. Biochemistry of Platinum Coordination Complexes in Cancer Chemotherapy

    1. Front Matter

      Pages 9-9
      PDF

    2. Overview

      • S. J. Lippard
      Pages 11-13

    4. Is DNA the Real Target of Antitumor Platinum Compounds?

      • J. P. Macquet, J. L. Butour, N. P. Johnson, H. Razaka, B. Salles, C. Vieussens et al.
      Pages 27-38

    5. Specific Binding of cis-Platinum Compounds to DNA and DNA Fragments

      • J. Reedijk, J. H. J. den Hartog, A. M. J. Fichtinger-Schepman, A. T. M. Marcelis
      Pages 39-63

  4. Pharmacology and Pharmacodynamics of Platinum Coordination Complexes in Cancer Chemotherapy

    1. Front Matter

      Pages 65-65
      PDF

    2. Overview

      • C. L. Litterst
      Pages 67-70

    4. Clinical Pharmacokinetics of Diammine [1,1-Cydobutanedicarboxylato (2-)]-0,0′-Platinum (CBDCA)

      • P. V. Woolley, V. M. Priego, P. V. T. Luc, A. Rahman, P. S. Schein
      Pages 82-89

    5. Biliary Excretion, Renal Handling and Red Cell Uptake of Cisplatin and CBDCA in Animals

      • Z. H. Siddik, D. R. Newell, F. E. Boxall, M. Jones, K. G. McGhee, K. R. Harrap
      Pages 90-102

    7. Clinical Pharmacokinetics of cis-Dichloro-trans-Dihydroxy-bis(Isopropylamine)Platinum(IV)

      • L. Pendyala, J. W. Cowens, S. Madajewicz, P. J. Creaven
      Pages 114-125

    8. Disposition of Cisplatin vs Total Platinum in Animals and Man

      • L. A. Sternson, A. J. Repta, H. Shih, K. J. Himmelstein, T. F. Patton
      Pages 126-147

  5. Toxicology of Platinum Coordination Complexes in Cancer Chemotherapy

    1. Front Matter

      Pages 149-149
      PDF

    2. Overview

      • M. P. Hacker
      Pages 151-153

    3. Diethyldithiocarbamate and cis-Platinum Toxicity

      • R. F. Borch, D. L. Bodenner, J. C. Katz
      Pages 154-164
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About this book

The idea for convening a Fourth International Symposium on Platinum Coordination Complexes in Cancer Chemotherapy was born in an assembly of researchers from the Vermont Regional Cancer Center and the Norris Cotton Cancer Center who shared a common interest in metal complexes. It was agreed by those assembled that sufficient time had passed since the Third International Symposium on Platinum Coor­ dination Complexes in Cancer Chemotherapy held in 1976 at the Wadley Institutes of Molecular Medicine in Dallas, Texas, during which several advances in the chemistry, biochemistry, pharmacology and clinical use of platinum complexes had occurred, to warrant a fourth symposium. Furthermore, intensive investigations in progress were bringing sophisticated methodologies to bear on the problems in the field, clinical trials were yielding interesting results, and unique approaches to cancer therapy were being designed. Therefore, an organizing committee was formed and planning culminated in the symposium which was held in Burlington, Vermont, June 22-24, 1983.
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Keywords

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Editors and Affiliations

  • Vermont Regional Cancer Center and Department of Pharmacology, University of Vermont, Burlington, USA

    Miles P. Hacker

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Bibliographic Information

  • Book Title: Platinum Coordination Complexes in Cancer Chemotherapy

  • Book Subtitle: Proceedings of the Fourth International Symposium on Platinum Coordination Complexes in Cancer Chemotherapy convened in Burlington, Vermont by the Vermont Regional Cancer Center and the Norris Cotton Cancer Center, June 22–24, 1983

  • Editors: Miles P. Hacker, Evan B. Douple, Irwin H. Krakoff

  • Series Title: Developments in Oncology

  • DOI: https://doi.org/10.1007/978-1-4613-2837-7

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Martinus Nijhoff Publishing, Boston 1984

  • Softcover ISBN: 978-1-4612-9792-5Published: 23 November 2011

  • eBook ISBN: 978-1-4613-2837-7Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: 408

  • Topics: Oncology

  • Industry Sectors: Biotechnology, Health & Hospitals, Pharma

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Access via your institution

Buy it now

eBook USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

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