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Biology and Therapy of Acute Leukemia

Proceedings of the Seventeenth Annual Detroit Cancer Symposium Detroit, Michigan — April 12–13, 1984

  • Conference proceedings
  • © 1985

Overview

Editors:
  1. Laurence Baker

    1. Wayne State University, Detroit, USA

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  2. Frederick Valeriote

    1. Wayne State University, Detroit, USA

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  3. Voravit Ratanatharathorn

    1. Wayne State University, Detroit, USA

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Part of the book series: Developments in Oncology (DION, volume 33)

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Table of contents (17 papers)

  1. Front Matter

    Pages i-xii
    Download chapter PDF

  2. The Impact of Treatment on the Natural History of Acute Leukemia

    • Emil J Freireich
    Pages 1-7

  3. Experimental Rationale for Therapy in the Treatment of Acute Leukemia

    • Frederick A. Valeriote
    Pages 8-42

  4. Clinical Laboratory Methods Used for the Classification of Acute Leukemia

    • Margarita Palutke
    Pages 43-52

  5. HTLV-II and Human Leukemia

    • William Wachsman, Judith C. Gasson, David W. Golde, Irvin S. Y. Chen
    Pages 53-64

  6. Oncogene Expression and Arrangement in Human Leukemia

    • Steven J. Collins
    Pages 65-76

  7. Clonal Variation and Phenotypic Progression in Retrovirus Transformed Leukemia Cells

    • David L. Hines
    Pages 77-96

  8. Chemotherapeutic Agents as Differentiation Inducers

    • Alexander Bloch
    Pages 97-105

  9. Modes of Drug Resistance in Acute Leukemias

    • David Kessel
    Pages 106-112

  10. The Evolution of Therapy for Acute Lymphatic Leukemia in Children

    • Teresa J. Vietti, James Boyett
    Pages 113-141

  11. Prognostic Factors in Childhood Acute Lymphoblastic Leukemia: Correlation with Treatment Response

    • Y. Ravindranath
    Pages 142-157

  12. Clinical Trials in Adult ANLL: An Overview

    • Michael Rooney
    Pages 158-174

  13. Allogeneic Marrow Transplantation for Acute Nonlymphoblastic Leukemia in Adults

    • Frederick R. Appelbaum, E. Donnall Thomas
    Pages 175-187

  14. Treatment Choices for Patients with Acute Nonlymphocytic Leukemia in Remission: Chemotherapy and Bone Marrow Transplantation

    • Harvey D. Preisler
    Pages 188-195

  15. Autologous Bone Marrow Transplantation in Acute Leukemia

    • Voravit Ratanatharathorn, Chatchada Karanes, Joe Mahoney, Frederick R. Appelbaum
    Pages 196-212

  16. Treatment of Leukemia and Lymphoma with Biological Response Modifiers

    • Kenneth A. Foon
    Pages 213-229

  17. Transfusion Therapy for the Support of Leukemia Patients

    • Chatchada Karanes, Voravit Ratanatharathorn
    Pages 230-244

  18. Leukemia: Hemorrhagic and Thrombotic Complications

    • John Penner
    Pages 245-259
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Keywords

About this book

This year notes two major changes in the annual Detroit Cancer Symposium. The first is our intention of selecting top­ ics of broad interest to the cancer community and examining the subject from both a basic laboratory and clinical viewpoint. In this way, the importance of both elements of cancer research are noted and the interplay between them emphasized. Further, we believe that Symposia such as this act to stimulate the basic scientist and clinician to continue their studies with the know­ ledge of the impact that each has upon the other and the nec­ essary cooperation required to solve the cancer problem. The second change is the publication of this Symposium. The pre­ vious sixteen were not committed to manuscript form. Given the change in format and intent of the series, we believe that this and subsequent volumes will make important contributions to the cancer literature. The topic of "Biology and Therapy of Acute Leukemia" was chosen for the first Symposium because of its historical signif­ icance in cancer chemotherapy. The therapeutic rationale for human leukemia is the result of understanding the basic tumor biology largely derived from transplantable leukemias in exper­ imental animals. It is through these models, as discussed by Dr. Fred Valeriote, that we learned the cellular kinetics of leukemia, the antileukemic effects of new agents and the ef­ fect of growth perturbation by various chemotherapeutic agents and their combinations.

Editors and Affiliations

  • Wayne State University, Detroit, USA

    Laurence Baker, Frederick Valeriote, Voravit Ratanatharathorn

Bibliographic Information

  • Book Title: Biology and Therapy of Acute Leukemia

  • Book Subtitle: Proceedings of the Seventeenth Annual Detroit Cancer Symposium Detroit, Michigan — April 12–13, 1984

  • Editors: Laurence Baker, Frederick Valeriote, Voravit Ratanatharathorn

  • Series Title: Developments in Oncology

  • DOI: https://doi.org/10.1007/978-1-4613-2609-0

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Martinus Nijhoff Publishing, Boston 1985

  • Hardcover ISBN: 978-0-89838-728-5Published: 31 May 1985

  • Softcover ISBN: 978-1-4612-9633-1Published: 09 January 2012

  • eBook ISBN: 978-1-4613-2609-0Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XII, 259

  • Topics: Oncology

  • Industry Sectors: Biotechnology, Health & Hospitals, Pharma

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