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Handbook of the Hemopoietic Microenvironment

  • Book
  • © 1989

Overview

Editors:
  1. Mehdi Tavassoli

    1. Veterans Administration Medical Center, University of Mississippi School of Medicine, Jackson, USA

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Part of the book series: Contemporary Biomedicine (CB, volume 9)

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-xxii
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  2. Hemopoietic Microenvironments

    • John J. Trentin
    Pages 1-86

  3. Molecular and Cellular Traffic Across the Marrow Sinuses

    • Marshall A. Lichtman, Charles H. Packman, Louis S. Constine
    Pages 87-140

  4. In Vivo Microscopy of Hemopoietic Tissue

    • Robert S. McCuskey
    Pages 141-155

  5. Fatty Involution of Marrow and the Role of Adipose Tissue in Hemopoiesis

    • Mehdi Tavassoli
    Pages 157-187

  6. Hematopoiesis on Artificial Membranes

    • William H. Knospe
    Pages 189-218

  7. Cellular Components of Stroma In Vivo In Comparison With In Vitro Systems

    • Mati Shaklai
    Pages 219-251

  8. Stromal Cells in Long-Term Bone Marrow Cultures

    • Peter J. Quesenberry
    Pages 253-285

  9. Cultured Stromal Cell Lines from Hemopoietic Tissues

    • Dov Zipori
    Pages 287-333

  10. Cellular Interactions in the Regulation of Human Hemopoiesis In Vitro

    • Joao L. Ascensao, Esmail D. Zanjani
    Pages 335-368

  11. The Collagenous Hemopoietic Microenvironment

    • Renate E. Gay, C. W. Prince, K. S. Zuckerman, S. Gay
    Pages 369-398

  12. The Hemopoietic Extracellular Matrix

    • Kenneth S. Zuckerman, Charles W. Prince, Steffen Gay
    Pages 399-432

  13. Bone Marrow Microenvironment

    • N. T. Shahidi, W. B. Ershler
    Pages 433-444

  14. Back Matter

    Pages 445-453
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Keywords

About this book

In 1868, Ernst Neumann recognized that blood cells re­ quire continuous replenishment during postnata1life. Before him, the assumption was that cells of the blood, like nerves once formed in the embryo, remain in the body throughout life. Neumann also recognized that this process occurred within the bone marrow, because this tissue provided a fa­ vorable environment for proliferation and differentiation of blood cell precursors. Vera Danchakoff, the Russian embryologist working in the US, in 1916 made an analogy to the soil and the seed. Bone marrow forms the soil, providing a favorable environment for the growth of seed, the hemopoietic stem cell, and other progenitor cells. Imagine in the remote past a heap of similar tree seeds. These seeds develop in our moderate climate into a tall and many branched tree. Suppose the wind bears a part of the seeds away and brings them to a land possessing different environmental conditions, we will say the arc­ tic lands. There the seeds may develop but they may pro­ duce trees no higher than our moss.

Editors and Affiliations

  • Veterans Administration Medical Center, University of Mississippi School of Medicine, Jackson, USA

    Mehdi Tavassoli

Bibliographic Information

  • Book Title: Handbook of the Hemopoietic Microenvironment

  • Editors: Mehdi Tavassoli

  • Series Title: Contemporary Biomedicine

  • DOI: https://doi.org/10.1007/978-1-4612-4494-3

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1989

  • Hardcover ISBN: 978-0-89603-147-0Published: 13 November 1989

  • Softcover ISBN: 978-1-4612-8845-9Published: 02 August 2013

  • eBook ISBN: 978-1-4612-4494-3Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XXII, 454

  • Topics: Hematology

  • Industry Sectors: Biotechnology, Health & Hospitals, Pharma

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