Purines in Cellular Signaling

Adenosine Receptors and Effector Systems

1. Front Matter

   Pages 1-1

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2. Adenosine Agonists and Antagonists

   • J. W. Daly

   Pages 3-12

3. Intracellular and Extracellular Metabolism of Adenosine and Adenine Nucleotides

   • D. Pearson, L. L. Slakey

   Pages 13-19

4. Adenosine Deaminase and Adenosine Transport Systems in the CNS

   • J. D. Geiger, R. A. Padua, J. I. Nagy

   Pages 20-25

5. Transport Systems for Adenosine in Mammalian Cell Membranes

   • A. S. Clanachan, F. E. Parkinson

   Pages 26-32

6. Formation of Adenosine in the Heart from Extracellular Adenine Nucleotides

   • J. Schrader, M. M. Borst, M. Kelm, B. Bading, K. F. Bürrig

   Pages 33-40

7. Central Nervous System Effects of Adenosine

   • J. W. Phillis

   Pages 41-47

8. Adenosine Receptor Sub-types in Isolated Tissues: Antagonist Studies

   • M. G. Collis

   Pages 48-53

9. Molecular Probes for Adenosine Receptors

   • K. A. Jacobson

   Pages 54-64

10. Purification of A1 Adenosine Receptor of Rat Brain Membranes by Affinity Chromatography

    • H. Nakata

    Pages 65-68

11. Characteristics of A1 Adenosine Receptors and Guanine Nucleotide Binding Proteins Co-Purified from Bovine Brain

    • J. Linden, R. Munshi, M. L. Arroyo, A. Patel

    Pages 69-72

12. Antagonist Radioligand Binding to Solubilized Porcine Atrial A1 Adenosine Receptors

    • M. Leid, P. H. Franklin, T. F. Murray

    Pages 73-77

13. Isolation of an Adenosine Binding Protein Which Has Properties Expected of the A1 Adenosine Receptor

    • K. Ravid, J. M. Lowenstein

    Pages 78-81

14. Identification of the A2 Adenosine Receptor Binding Subunit by Photoaffinity Crosslinking

    • W. W. Barrington, K. A. Jacobson, A. J. Hutchison, M. Williams, G. L. Stiles

    Pages 82-85

15. Human Placental Adenosine A2-Like Binding Sites Properties and Homology with Mammalian and Avian Stress Proteins

    • K. A. Hutchison, B. Nevins, F. Perini, I. H. Fox

    Pages 86-89

16. Cardiac Interstitial Fluid Adenosine in Normoxia and Hypoxia

    • R. M. Berne

    Pages 90-95

17. Rationale for the Use of Adenosine in the Diagnosis and Treatment of Cardiac Arrhythmias

    • L. Belardinelli, A. Pelleg

    Pages 95-99

18. The Central Adenosine System as a Therapeutic Target in Stroke

    • P. J. Marangos, D. Von Lubitz, L. P. Miller, J. L. Daval, J. Deckert

    Pages 100-107

19. Adenosine-Mediated Vasoconstriction in the Skin Microcirculation

    • K. G. Proctor, I. Stojanov

    Pages 108-113