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Levodopa-Induced Dyskinesia in Parkinson's Disease

  • Susan H. Fox
  • Jonathan M. Brotchie

Table of contents

  1. Front Matter
    Pages i-xii
  2. Panagiotis Zis, Kallol Ray Chaudhuri, Michael Samuel
    Pages 1-16
  3. Christopher G. Goetz, Carlo Colosimo
    Pages 17-31
  4. Miguel Coelho, Joaquim J. Ferreira
    Pages 33-50
  5. Jee-Young Lee, Beom S. Jeon
    Pages 51-68
  6. Renato P. Munhoz, Michael S. Okun
    Pages 89-107
  7. Wai Kin D. Ko, Matthieu Bastide, Erwan Bezard
    Pages 109-134
  8. Marcelo Merello, Inés Trigo Damas, José A. Obeso
    Pages 135-146
  9. Philippe Huot
    Pages 147-169
  10. Vincent A. Jourdain, Nicolas Morin, Thérèse Di Paolo
    Pages 171-197
  11. Elisabetta Tronci, Camino Fidalgo, Manolo Carta
    Pages 199-212
  12. Tom H. Johnston, Paula Ravenscroft, Michael P. Hill
    Pages 213-227
  13. Barbara Picconi, Paolo Calabresi
    Pages 229-243
  14. Andrea Giuffrida, Alex Martinez
    Pages 245-264
  15. Maryka Quik, Tanuja Bordia, Danhui Zhang, Xiomara Perez
    Pages 285-300
  16. Susan H. Fox, Isabelle Boileau-Boire
    Pages 301-333
  17. Veronica Francardo, M. Angela Cenci
    Pages 335-353
  18. Back Matter
    Pages 361-368

About this book

Introduction

This book aims to provide a single reference source on levodopa-induced dyskinesias (LID) from ‘bench to bedside’.

Initial chapters review the clinical features and phenomenology of LID with video examples; epidemiology and genetic risk factors for LID are covered as a background to understanding risk factors for developing LID. The following chapters cover the latest preclinical studies aiming to understand the pathophysiology of LID at the cellular, neurochemical, neurophysiological and circuitry level with detailed discussion of mechanisms and future directions to take the field forward; clinical studies from phase II to phase IV; ongoing RCTs in LID; and evidence-based medicine reviews of treatment options. 

Levodopa-Induced Dyskinesia in Parkinson’s Disease is aimed at an international audience of movement disorder neurologists; neuroscientists; trainees; and graduate and post-graduate students.​

Keywords

Parkinson's disease clinical trial dyskinesia levodopa levodopa-induced dyskinesia parkinsonism preclinical study

Editors and affiliations

  • Susan H. Fox
    • 1
  • Jonathan M. Brotchie
    • 2
  1. 1.Toronto Western HospitalTorontoCanada
  2. 2.Toronto Western HospitalTorontoCanada

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4471-6503-3
  • Copyright Information Springer-Verlag London 2014
  • Publisher Name Springer, London
  • eBook Packages Medicine
  • Print ISBN 978-1-4471-6502-6
  • Online ISBN 978-1-4471-6503-3
  • Buy this book on publisher's site
Industry Sectors
Pharma
Health & Hospitals
Biotechnology