The Heart and Circulation

An Integrative Model

  • Branko Furst

Table of contents

  1. Front Matter
    Pages i-xxix
  2. Embryonic Circulation

    1. Front Matter
      Pages 1-1
    2. Branko Furst
      Pages 3-10
    3. Branko Furst
      Pages 11-19
    4. Branko Furst
      Pages 37-40
    5. Branko Furst
      Pages 47-51
    6. Branko Furst
      Pages 53-56
    7. Branko Furst
      Pages 57-60
    8. Branko Furst
      Pages 61-64
    9. Branko Furst
      Pages 65-85
  3. Mature Circulation

    1. Front Matter
      Pages 93-93
    2. Branko Furst
      Pages 95-109
    3. Branko Furst
      Pages 111-131
    4. Branko Furst
      Pages 143-163
    5. Branko Furst
      Pages 165-179
    6. Branko Furst
      Pages 181-187
    7. Branko Furst
      Pages 189-202
    8. Branko Furst
      Pages 203-210
    9. Branko Furst
      Pages 211-219
  4. Back Matter
    Pages 221-226

About this book


What drives the circulation?  In this comprehensive review of existing circulation models, the conventional view that the heart is a pressure-propulsion pump is challenged. The existing models fail to explain an increasing number of observed circulatory phenomena.


A unifying circulation model is proposed in which the blood, responding to metabolic demands of the tissues, is the primary regulator of cardiac output. This new model arises from accumulated clinical and experimental evidence. The heart, rather than being an organ of blood propulsion, assumes a secondary role and generates pressure by impeding the flow of blood. This is supported by examples from the fields of early embryonic circulation, comparative phylogeny, functional morphology, exercise physiology and a range of clinical scenarios.


The Heart and Circulation: An Integrative Model offers a paradigm shift in the understanding of circulatory phenomena. It will become a valuable resource for all those clinicians, researchers, educators and students who, having been confronted with the paradox of the circulation, are looking for a broader interpretation.


Cardiovascular Hemodynamics Early Embryo Circulation Heart Rate Perturbations

Authors and affiliations

  • Branko Furst
    • 1
  1. 1.Department of AnesthesiologyAlbany Medical CollegeAlbanyUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag London 2014
  • Publisher Name Springer, London
  • eBook Packages Medicine
  • Print ISBN 978-1-4471-5276-7
  • Online ISBN 978-1-4471-5277-4
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals