Molecular Pathology of Endocrine Diseases

1. Front Matter

   Pages i-xi

   PDF

2. General Endocrine Molecular Pathology

   1. Front Matter

      Pages 1-1

      PDF

   2. Molecular Oncogenesis

      • Jennifer L. Hunt

      Pages 3-8

   3. Systematic Autoimmune Diseases

      • Sigrid Wayne

      Pages 9-19

   4. MicroRNAs in Endocrine Diseases

      • Simion Chiosea

      Pages 21-24

3. Thyroid Diseases

   1. Front Matter

      Pages 26-26

      PDF

   2. Clinical Detection and Treatment of Thyroid Diseases

      • Jamie C. Mitchell, Mira Milas

      Pages 27-35

   3. Autoimmune Thyroid Diseases

      • Ashraf Khan, Otto Walter

      Pages 37-45

   4. Benign Nodular Thyroid Disease

      • Jennifer L. Hunt

      Pages 47-50

   5. Fine Needle Aspiration: Present and Future

      • Zubair W. Baloch, Virginia A. LiVolsi

      Pages 51-56

   6. Well-Differentiated Papillary Thyroid Carcinoma

      • Lori A. Erickson, Ricardo V. Lloyd

      Pages 57-71

   7. Well-Differentiated Thyroid Follicular Carcinoma

      • Todd G. Kroll

      Pages 73-93

   8. Poorly Differentiated and Undifferentiated Thyroid Carcinomas

      • Jennifer L. Hunt, Virginia A. LiVolsi

      Pages 95-101

   9. Medullary Thyroid Carcinoma

      • Ronald A. DeLellis

      Pages 103-121

   10. Unusual Thyroid Tumors

       • Jennifer L. Hunt

       Pages 123-126

   11. Hematopoietic Tumors of the Thyroid

       • Lawrence Tsao, Eric Hsi

       Pages 127-135

4. Parathyroid Diseases

   1. Front Matter

      Pages 138-138

      PDF

   2. Clinical Detection and Treatment of Parathyroid Diseases

      • Michael T. Stang, Sally E. Carty

      Pages 139-150

   3. Nonneoplastic Parathyroid Diseases

      • Lori A. Erickson

      Pages 151-157

   4. Neoplastic Parathyroid Diseases

      • Raja R. Seethala

      Pages 159-166

The past two decades have seen an ever accelerating growth in knowledge about molecular pathology of human diseases, which received a large boost with the sequencing of the human genome in 2003. Mole- lar diagnostics, molecular targeted therapy, and genetic therapy are now routine in many medical centers. The molecular field now impacts every field in medicine, whether clinical research or routine patient care. There is a great need for basic researchers to understand the potential clinical implications of their research whereas private practice clinicians of all types (general internal medicine and internal medicine specialists, medical oncologists, radiation oncologists, surgeons, pediatricians, family practitioners), clinical inves- gators, pathologists and medical laboratory directors, and radiologists require a basic understanding of the fundamentals of molecular pathogenesis, diagnosis, and treatment for their patients. Traditional textbooks in molecular biology deal with basic science and are not readily applicable to the medical setting. Most medical textbooks that include a mention of molecular pathology in the clinical setting are limited in scope and assume that the reader already has a working knowledge of the basic science of molecular biology. Other texts emphasize technology and testing procedures without integrating the clinical perspective. There is an urgent need for a text that fills the gap between basic science books and clinical practice.

• Endocrine
• Neuroendocrine Lesions
• Pancreatic Neuroendocrine Tumors
• Parathyroid Diseases
• Pituitary Diseases
• Thyroid Diseases
• carcinoma
• cell
• diagnostics
• growth
• internal medicine
• molecular biology
• molecular pathology
• pathogenesis

From the reviews:

“This book focuses on the newest molecular discoveries and their role in the pathogenesis, diagnosis, and treatment of various endocrine disorders, incorporating a generous number of images and tables. … useful to medical students, pathology assistant students, and residents, as well as other healthcare professionals who wish to broaden their knowledge of molecular pathology. … it correlates the histologic, clinical, and molecular features of endocrine diseases, giving a more complete picture of the problem. … a useful complement to everyday practice and study.” (Luka Ozretic, Doody’s Review Service, July, 2010)

• Pathology Service, WRN202, Massachusetts General Hospital, Boston, USA

  Jennifer L. Hunt

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