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  • © 2009

Astrocytes in (Patho)Physiology of the Nervous System

  • Presents latest research of the role of astrocytes in the physiology and pathophysiology of brain

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eBook USD 179.00
Price excludes VAT (USA)
  • ISBN: 978-0-387-79492-1
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book USD 229.00
Price excludes VAT (USA)
Hardcover Book USD 299.99
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Table of contents (26 chapters)

  1. Front Matter

    Pages i-xix
  2. Astrocyte Heterogeneity or Homogeneity?

    • Harold K. Kimelberg
    Pages 1-25
  3. Neural Stem Cells Disguised as Astrocytes

    • Rebecca A. Ihrie, Arturo Alvarez-Buylla
    Pages 27-47
  4. Neurotransmitter Receptors in Astrocytes

    • Alexei Verkhratsky
    Pages 49-67
  5. Specialized Neurotransmitter Transporters in Astrocytes

    • Yongjie Yang, Jeffrey D. Rothstein
    Pages 69-105
  6. Connexin Expression (Gap Junctions and Hemichannels) in Astrocytes

    • Eliana Scemes, David C. Spray
    Pages 107-150
  7. Regulation of potassium by glial cells in the centralnervous system

    • Paulo Kofuji, Eric A. Newman
    Pages 151-175
  8. Energy and Amino Acid Neurotransmitter Metabolism in Astrocytes

    • Helle S. Waagepetersen, Ursula Sonnewald, Arne Schousboe
    Pages 177-200
  9. Calcium ion signaling in astrocytes

    • Joachim W. Deitmer, Karthika Singaravelu, Christian Lohr
    Pages 201-224
  10. Synaptic Information Processing by Astrocytes

    • Gertrudis Perea, Alfonso Araque
    Pages 287-300
  11. Mechanisms of transmitter release from astrocytes

    • Erik B. Malarkey, Vladimir Parpura
    Pages 301-350
  12. Release of Trophic Factors and Immune Molecules from Astrocytes

    • Ying Y. Jean, Issa P. Bagayogo, Cheryl F. Dreyfus
    Pages 351-381
  13. Molecular approaches for studying astrocytes

    • Todd Fiacco, Kristi Casper, Elizabeth Sweger, Cendra Agulhon, Sarah Taves, Suzanne Kurtzer-Minton et al.
    Pages 383-405
  14. The tripartite synapse

    • Michael M. Halassa, Philip G. Haydon
    Pages 407-415
  15. Glia-derived D-serine and synaptic plasticity

    • Magalie Martineau, Stéphane H.R. Oliet, Jean-Pierre Mothet
    Pages 417-441
  16. Astrocyte control of blood flow

    • Grant R.J. Gordon, Sean J. Mulligan, Brian A. MacVicar
    Pages 461-486

About this book

Due to their lack of electrical excitability, astrocytes, a subtype of glial cell, have long been neglected as active participants in intercellular communication within the central nervous system. Astrocytes, however, possess a diverse assortment of ion channels,
neurotransmitter receptors, and transport mechanisms that enable them to respond to many of the same signals that act on neurons. Astrocytes in (Patho)Physiology of the Nervous System provides readers with a comprehensive description of the physiological roles astrocytes play in regulating neuronal activity and their critical involvement in
pathophysiological states of the nervous system, including gliomas, Alexander's disease, and epilepsy. This book will be particularly useful for researchers, students, and workers in the field of neurobiology and cell biology.

About the authors:

Vladimir Parpura, M.D., Ph.D holds both a medical degree, awarded from the University of Zagreb in Croatia in 1989, and a doctorate, received in Neuroscience and Zoology from Iowa State University in 1993.  He has held faculty appointments at the Department of Zoology and Genetics, Iowa State University and the Department of Cell Biology and Neuroscience, University of California Riverside. He is presently an Associate Professor in the Department of Neurobiology, University of Alabama Birmingham.  His current research focuses on understanding the modulation of calcium-dependent glutamate release from astrocytes.

Philip G. Haydon, Ph.D received his doctorate from the University of Leeds, England in 1982.  He has held faculty appointments at the Department of Zoology and Genetics, Iowa State University, the Department of Neuroscience at the University of Pennsylvania, and has recently moved to Tufts University School of Medicine as Professor and Chair of the Department of Neuroscience. His research focuses on the role of astrocytes in the regulation of synapses, neuronal networks and behavior as well as how these glial cells contribute to neurological disorders.

Keywords

  • Nervous System
  • astrocytes
  • glial cell
  • information processing
  • neurons
  • physiology
  • regulation

Bibliographic Information

  • Book Title: Astrocytes in (Patho)Physiology of the Nervous System

  • Editors: Philip G. Haydon, Vladimir Parpura

  • DOI: https://doi.org/10.1007/978-0-387-79492-1

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer-Verlag US 2009

  • Hardcover ISBN: 978-0-387-79491-4

  • Softcover ISBN: 978-1-4899-7911-7

  • eBook ISBN: 978-0-387-79492-1

  • Edition Number: 1

  • Number of Pages: XX, 738

  • Number of Illustrations: 87 b/w illustrations, 32 illustrations in colour

  • Topics: Neuroscience, Cell Biology

  • Industry Sectors: Biotechnology, Health & Hospitals, Pharma

Buying options

eBook USD 179.00
Price excludes VAT (USA)
  • ISBN: 978-0-387-79492-1
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book USD 229.00
Price excludes VAT (USA)
Hardcover Book USD 299.99
Price excludes VAT (USA)