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  • Book
  • © 2005

Atherosclerosis: Diet and Drugs

Editors:

  1. Arnold Eckardstein

    1. Institute of Clinical Chemistry, University Hospital of Zurich, Zürich, Switzerland

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Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 170)

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Table of contents (30 chapters)

  1. Targets of Future Anti-Atherosclerotic Drug Therapy

    2. Inhibition of Lipoprotein Lipid Oxidation

      • O. Cynshi, R. Stocker
      Pages 563-590

    3. Correction of Insulin Resistance and the Metabolic Syndrome

      • D. Müller-Wieland, J. Kotzka
      Pages 591-617

    4. Protection of Endothelial Function

      • L.E. Spieker, T.F. Lüscher
      Pages 619-644

    6. Modulation of Macrophage Function and Metabolism

      • S. Bellosta, F. Bernini
      Pages 665-695

    8. Autoimmune Mechanisms of Atherosclerosis

      • K. Mandal, M. Jahangiri, Q. Xu
      Pages 723-743

    9. Drug Therapies to Prevent Coronary Plaque Rupture and Erosion: Present and Future

      • P.T. Kovanen, M. Mäyränpää, K.A. Lindstedt
      Pages 745-776

    10. Reciprocal Role of Vasculogenic Factors and Progenitor Cells in Atherogenesis

      • T. Murayama, O.M. Tepper, T. Asahara
      Pages 777-783

    11. Gene Therapy of Atherosclerosis

      • E. Vähäkangas, S. Ylä-Herttuala
      Pages 785-807

  2. Back Matter

    Pages 809-816
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About this book

Cardiovascular diseases continue to be the leading cause of death in the - jority of industrialized countries. The most frequent underlying pathology, namely atherosclerosis, and its clinical sequelae, namely coronary heart d- ease, cerebrovascular disease and peripheral artery disease, remain common although for a long time we have been made aware of avoidable or mo- ?able etiological factors such as smoking, fat-rich diet or lack of exercise, and although these adverse lifestyle factors have been extensively addressed by population-wide primary prevention programs. Cardiovascular morbidity and mortality also remain high despite successful anti-hypertensive and lipid lowering drug therapies which help to reduce cardiovascular morbidity and mortality by about 30% in both secondary and tertiary prevention settings. This can partly be explained by the increasing life expectancy and growing p- portionofelderly people,especiallyinEuropeandNorthAmerica. Inaddition, the World Health Organization makes the alarming prediction that probably in response to the spreading of western dietary behavior and lack of exercise resulting in an increasing prevalence of diabetes, dyslipidemia and hypert- sion, cardiovascular diseases rather than infectious diseases will become the most frequent cause of death worldwide. This volume of the Handbook of Experimental Pharmacology entitled “Atherosclerosis” is divided into four parts and intends to give an overview on the pathogenesis of atherosclerosis, established treatment and prevention regimen, and of perspectives for the development of new treatment modalities.
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Keywords

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Editors and Affiliations

  • Institute of Clinical Chemistry, University Hospital of Zurich, Zürich, Switzerland

    Arnold Eckardstein

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Bibliographic Information

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Buy it now

eBook USD 429.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 549.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 549.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

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