Name: Peptides for the New Millennium
ISBN: 978-0-306-46881-0

Editors:

Gregg B. Fields⁰,
James P. Tam¹,
George Barany²

Gregg B. Fields
1. Department of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, USA
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James P. Tam
1. Department of Microbiology and Immunology, Vanderbilt University Medical School, Nashville, USA
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George Barany
1. Departments of Chemistry and Laboratory Medicine & Pathology, University of Minnesota, Minneapolis, USA
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Part of the book series: American Peptide Symposia (APSY, volume 6)

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Table of contents (318 papers)

Synthetic Methodologies (including Large-Scale Synthesis)
1. Nsc- and Fmoc-amino acids for automated solid-phase peptide synthesis: Comparative study of the stability in various conditions
  
  Yeon Sun Lee, Hyun Jin Lee, Doyoung Lee, Hack-Joo Kim
  
  Pages 53-54
2. In situ generation of Fmoc amino acid chlorides for extremely difficult couplings to sterically hindered secondary amines in solid-phase peptide synthesis
  
  Eliezer Falb, Tamar Yechezkel, Yosphe Salitra, Gary Gellerman, Dan Muller, Chaim Gilon
  
  Pages 55-57
3. Evaluation of ivDde as a quasi-orthogonal protecting group for Fmoc solid-phase peptide synthesis
  
  R. Randy Wilhelm, Ananth Srinivasan, Michelle A. Schmidt
  
  Pages 58-59
4. Nⁱⁿ-4-Nitrobenzenesulfonyl (Nbs): A new protecting group for the indole moiety of tryptophan
  
  Aydar N. Sabirov, Vladimir V. Samukov, Pavel I. Pozdnyakov, Hack-Joo Kim
  
  Pages 60-61
5. Practical asymmetric synthesis of β-substituted glutamic acids
  
  Vadim A. Soloshonok, Chaozhong Cai, Victor J. Hruby
  
  Pages 62-63
6. Formation of substituted aromatic rings in amino acid systems via ruthenium activated SNAr reactions
  
  Chris W. West, Jim W. Janetka, Daniel H. Rich
  
  Pages 64-65
7. O-Acetyl-L-homoserine: A versatile synthon for the synthesis of L-homoserine peptides and 3-amino-2-pyrrolidinones
  
  Guenter Knaup, Karlheinz Drauz, Michael Schwarm
  
  Pages 66-67
8. Asymmetric synthesis of free unusual β aminoacid esters via Yb(OTf)3-caalyzed C-C bond formation and simultaneous deprotection/purification
  
  Guigen Li, Sun Hee Kim, Han-Xun Wei, Jason D. Hook, Keith A. Fitzgerald
  
  Pages 68-70
9. High yield synthesis of heterocyclic β-substituted alanine derivatives
  
  Paula M. T. Ferreira, Hernâni L. S. Maia, Luís S. Monteiro
  
  Pages 70-71
10. Synthesis of (2S,4R)-4-aminoethyl-L-Pro and (2S,4R)-4-carboxymethyl-L-Pro from (2S,4R)-N^α-Boc-4-hydroxy-L-Pro methyl ester
  
  Dewey G. McCafferty, Stephen L. Schneider, Bruce W. Erickson
  
  Pages 72-73
11. A highly effective method for synthesis of N^ω-substituted arginines
  
  Sotir Zakhariev, Zoltán Székely, Corrado Guarnaccia, Nikolinka Antcheva, Sándor Pongor
  
  Pages 74-75
12. Diffusion phenomena and reactivity using polymer supports: A principal investigation
  
  Wolfgang E. Rapp
  
  Pages 76-78
13. Solid-phase peptide synthesis in the N→C direction
  
  Nathalie Thieriet, Jordi Alsina, François Guibé, Fernando Albericio
  
  Pages 78-79
14. Diisopropylethylamine salts for protected amino acids: Direct synthesis of peptides on solid-phase
  
  Preeti Balse, Guoxia Han, Victor J. Hruby, Lele Sun
  
  Pages 80-81
15. Synthesis of phosphorylated CRE BP1(19-106) amide using a phosphopeptide thioester prepared directly by an Fmoc solid-phase method
  
  Saburo Aimoto, Koki Hasegawa, Xiangqun Li, Toru Kawakami
  
  Pages 82-83
16. Preparation of phosphohistidyl peptides via oxidative coupling of H-phosphonates
  
  Bennet J. Harding, W. Scott Dodson, Brian D. Bennett, William S. Marshall, Mark A. Jarosinski
  
  Pages 84-85
17. Preparation and incorporation into small peptides and combinatorial libraries of phosphohistidine analogs for study of prokaryotic two-component signal transduction systems
  
  Michael C. Pirrung, Sandra J. Drabik, Kurt V. Gothelf, Kenneth D. James, Tao Pei
  
  Pages 86-88
18. Synthesis of phosphonamides and thiophosphonamides by a one-pot activation-coupling-oxidation protocol
  
  Sheila D. Rushing, Robert P. Hammer
  
  Pages 89-90
19. Synthesis of phosphonopeptide and thiophosphonopeptide analogs as inhibitors of carboxypeptidase A
  
  Hong Fan, Yuhong Zhao, Larry Byers, Robert P. Hammer
  
  Pages 91-93
20. Application of solid-phase Ellman’s reagent for preparation of disulfide-paired isomers of α-conotoxin SI
  
  Balazs Hargittai, Loana Annis, George Barany
  
  Pages 94-95

About this book

“Have you tried peptides? Small proteins, the best in the land! Won’t you try peptides? Keep all your body processes in hand! For labor and lactation oxytocin you must buy! Enkephalin always gives a good runner’s high! So won’t you try peptides? Small proteins, the best in the land!” The above words [1], penned by Gary Gisselman to open Peptide Ångst: La Triviata, the opera which made its world premiere on July 1, 1999, also serve as a fitting charge to the th 16 American Peptide Symposium. This latest edition of a premier biennial series was held under the auspices of the American Peptide Society, June 26–July 1, 1999, at the Minneapolis Convention Center, Minneapolis,Minnesota, with the undersigned serving as Co-Chairs. The fortunate coincidence of the calendar allowed us to set as the theme “Peptides for the New Millennium”, and in our judgment, the approximately 1200 participants [2] who converged in the Twin Cities from academic and industrial institutions in 36 countries were treated to an exciting and stimulating conference that left most everyone with an enthusiastic vision for the future of our field. The present Proceedings volume should serve as a handy reference source and succinct snapshot of peptide science at essentially its century mark – the clock having started with the initial contributions of Emil Fischer and Th. Curtius.

Keywords

Editors and Affiliations

Department of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, USA

Gregg B. Fields
Department of Microbiology and Immunology, Vanderbilt University Medical School, Nashville, USA

James P. Tam
Departments of Chemistry and Laboratory Medicine & Pathology, University of Minnesota, Minneapolis, USA

George Barany

Bibliographic Information

Book Title: Peptides for the New Millennium
Book Subtitle: Proceedings of the 16th American Peptide Symposium June 26–July 1, 1999, Minneapolis, Minnesota, U.S.A.
Editors: Gregg B. Fields, James P. Tam, George Barany
Series Title: American Peptide Symposia
DOI: https://doi.org/10.1007/0-306-46881-6
Publisher: Springer Dordrecht
eBook Packages: Springer Book Archive
Copyright Information: Springer Science+Business Media Dordrecht 2002
Hardcover ISBN: 978-0-7923-6445-0Published: 31 August 2000
Softcover ISBN: 978-94-017-4185-9Published: 04 December 2014
eBook ISBN: 978-0-306-46881-0Published: 17 May 2006
Edition Number: 1
Number of Pages: LXVII, 829
Topics: Bioorganic Chemistry, Biochemistry, general, Organic Chemistry, Analytical Chemistry

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Peptides for the New Millennium

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Table of contents (318 papers)

Synthetic Methodologies (including Large-Scale Synthesis)

Nsc- and Fmoc-amino acids for automated solid-phase peptide synthesis: Comparative study of the stability in various conditions

In situ generation of Fmoc amino acid chlorides for extremely difficult couplings to sterically hindered secondary amines in solid-phase peptide synthesis

Evaluation of ivDde as a quasi-orthogonal protecting group for Fmoc solid-phase peptide synthesis

Nⁱⁿ-4-Nitrobenzenesulfonyl (Nbs): A new protecting group for the indole moiety of tryptophan

Practical asymmetric synthesis of β-substituted glutamic acids

Formation of substituted aromatic rings in amino acid systems via ruthenium activated SNAr reactions

O-Acetyl-L-homoserine: A versatile synthon for the synthesis of L-homoserine peptides and 3-amino-2-pyrrolidinones

Asymmetric synthesis of free unusual β aminoacid esters via Yb(OTf)3-caalyzed C-C bond formation and simultaneous deprotection/purification

High yield synthesis of heterocyclic β-substituted alanine derivatives

Synthesis of (2S,4R)-4-aminoethyl-L-Pro and (2S,4R)-4-carboxymethyl-L-Pro from (2S,4R)-N^α-Boc-4-hydroxy-L-Pro methyl ester

A highly effective method for synthesis of N^ω-substituted arginines

Diffusion phenomena and reactivity using polymer supports: A principal investigation

Solid-phase peptide synthesis in the N→C direction

Diisopropylethylamine salts for protected amino acids: Direct synthesis of peptides on solid-phase

Synthesis of phosphorylated CRE BP1(19-106) amide using a phosphopeptide thioester prepared directly by an Fmoc solid-phase method

Preparation of phosphohistidyl peptides via oxidative coupling of H-phosphonates

Preparation and incorporation into small peptides and combinatorial libraries of phosphohistidine analogs for study of prokaryotic two-component signal transduction systems

Synthesis of phosphonamides and thiophosphonamides by a one-pot activation-coupling-oxidation protocol

Synthesis of phosphonopeptide and thiophosphonopeptide analogs as inhibitors of carboxypeptidase A

Application of solid-phase Ellman’s reagent for preparation of disulfide-paired isomers of α-conotoxin SI

About this book

Keywords

Editors and Affiliations

Department of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, USA

Department of Microbiology and Immunology, Vanderbilt University Medical School, Nashville, USA

Departments of Chemistry and Laboratory Medicine & Pathology, University of Minnesota, Minneapolis, USA

Bibliographic Information

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Table of contents (318 papers)

Synthetic Methodologies (including Large-Scale Synthesis)

About this book

Keywords

Editors and Affiliations

Department of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, USA

Department of Microbiology and Immunology, Vanderbilt University Medical School, Nashville, USA

Departments of Chemistry and Laboratory Medicine & Pathology, University of Minnesota, Minneapolis, USA

Bibliographic Information

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