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Table of contents

  1. Front Matter
  2. Amy E. Tucker, Jimmy D. Ballard
    Pages 21-34
  3. Kirsten Sandvig, Sébastien Wälchli, Silje U. Lauvrak
    Pages 35-53
  4. David E. Saslowsky, Michael Kothe, Wayne I. Lencer
    Pages 55-67
  5. Sucharit Bhakdi, Iwan Walev, Matthias Husmann, Angela Valeva
    Pages 91-110
  6. Susanne Leis, Jenny Spindler, Jochen Reiter, Frank Breinig, Manfred J. Schmitt
    Pages 111-132
  7. Raffael Schaffrath, Friedhelm Meinhardt
    Pages 133-155
  8. Jeremy Bruenn
    Pages 157-174
  9. J. Michael Lord, Lynne M. Roberts
    Pages 215-233
  10. Back Matter

About this book

Introduction

Since the initial establishment of Robert Koch’s postulates in the nineteenth century, microbial protein toxins have been recognized as a major factor of bacterial and fungal virulence. An increasing number of proteins produced and secreted by various bacteria, yeasts and plants are extremely toxic and most of them developed remarkably "intelligent" strategies to enter, to penetrate and to finally kill a eukaryotic target cell by modifying or blocking essential cellular components.

This book describes the strategies employed by protein toxins to render their pro- and eukaryotic producers a selective growth advantage over competitors. In providing an up-to-date overview on the mode of protein toxin actions, it accommodates biomedically and biologically relevant toxin model systems. As a result, it significantly broadens our perspective on biochemical architecture and molecular ploy behind the lethal principles of pro- and eukaryotic toxins.

Keywords

Eukaryotic Target Cell Proliferation and Growth Control Protein Toxins bacteria cell pathogenesis proliferation protein proteins pseudomonas synthesis toxin virulence virus yeast

Bibliographic information

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