Inhibitors of Protein Kinases and Protein Phosphates

  • Lorenzo A. Pinna
  • Patricia T.W. Cohen

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 167)

Table of contents

  1. Front Matter
    Pages I-X
  2. General Aspects of PKs Inhibition

  3. Pharmacological Potential and Inhibitors of Individual Classes of Protein Kinases

    1. S. Kumar, S. M. Blake
      Pages 65-83
    2. M. Gaßel, C. Breitenlechner, S. Herrero, R. Engh, D. Bossemeyer
      Pages 85-124
    3. R. Battistutta, S. Sarno, G. Zanotti
      Pages 125-155
    4. D. H. Fong, D. L. Burk, A. M. Berghuis
      Pages 157-188
  4. Pharmacological Potential and Inhibitors of Individual Classes of Protein Phosphatases

    1. A. Cheng, N. Uetani, C. Lampron, M. L. Tremblay
      Pages 191-214
    2. N. P. H. Møller, H. S. Andersen, C. B. Jeppesen, L. F. Iversen
      Pages 215-262
  5. Inhibitors in Clinical Use or Advanced Clinical Trials

  6. Back Matter
    Pages 451-458

About this book


The aims of this volume are to highlight the tremendous pharmacological potential of protein kinase and protein phosphatase inhibitors, to provide a thorough overview of the most remarkable achievements in the field and to illustrate how beneficial these studies can be for the advancement of both basic knowledge on biological regulation and deregulation and for the clinical treatment of a wide spectrum of diseases. This goal is attained by contributions of leader investigators in the field, who address the issue from different angles.


Anticancer drugs Antidiabetes targets Calcineurin-Inhibitor Cell signalling Glycogen Immunosuppressants Signal transduction therapy

Editors and affiliations

  • Lorenzo A. Pinna
    • 1
  • Patricia T.W. Cohen
    • 2
  1. 1.Dipartimento di Chimica BiologicaUniversità di PadovaPadovaItaly
  2. 2.MRC Protein Phosphorylation Unit, School of Life SciencesUniversity of DundeeDundeeScotland, UK

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