© 2006

Advances in Network Electrophysiology

Using Multi-Electrode Arrays

  • Makoto Taketani
  • Michel Baudry

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Development of MEA for Cells, Acute Slices, and Cultured Tissues

    1. Front Matter
      Pages 1-1
    2. Jerome Pine
      Pages 3-23
    3. Michael Fejtl, Alfred Stett, Wilfried Nisch, Karl-Heinz Boven, Andreas Möller
      Pages 24-37
    4. James Whitson, Don Kubota, Ken Shimono, Yousheng Jia, Makoto Taketani
      Pages 38-68
    5. Marc Olivier Heuschkel, Corina Wirth, Esther-Marie Steidl, Bruno Buisson
      Pages 69-111
    6. David Hakkoum, Dominique Muller, Luc Stoppini
      Pages 112-126
    7. Walid Soussou, Ghassan Gholmieh, Martin Han, Ashish Ahuja, Dong Song, Min-Chi Hsiao et al.
      Pages 127-152
    8. John C. Chang, Bruce C. Wheeler
      Pages 153-189
  3. MEA Applications: Dissociated Cell Cultures

    1. Front Matter
      Pages 191-191
    2. Guenter W. Gross, Kamakshi V. Gopal
      Pages 193-214
    3. Steve M. Potter, Daniel A. Wagenaar, Thomas B. DeMarse
      Pages 215-242
    4. Michele Giugliano, Maura Arsiero, Pascal Darbon, Jürg Streit, Hans-Rudolf Lüscher
      Pages 243-273
    5. Ulrich Egert, Kathrin Banach, Thomas Meyer
      Pages 274-290
  4. MEA Applications: Acute/Cultured Slices

    1. Front Matter
      Pages 291-291
    2. Ghassan Gholmieh, Spiros Courellis, Vasilis Marmarelis, Michel Baudry, Theodore W. Berger
      Pages 293-320
    3. Elke Guenther, Thoralf Herrmann, Alfred Stett
      Pages 321-331
    4. Larry P. Gonzalez, Ken D. Marshall, Prashantha D. Holla, Anand Mohan
      Pages 332-354
    5. Jürg Streit, Anne Tscherter, Pascal Darbon
      Pages 377-408

About this book


This book book is an attempt to review the recent progress in both electronics and computational tools developed to analyze the functional operations of large ensembles of neurons and to provide the readers with a sense of the applications made possible by these technological tools. While considerable progress has been made over the last decades in our understanding of electrophysiological processes at the single channel, single

synapse, and single neuron levels, our understanding of electrophysiological

processes at the neuronal network level is still in its infancy.

This book includes:

  • Technological overviews of multi-electrode arrays (MEAs) and related electronics and software,
  • Applications of MEAs to study ensemble activity of dissociated cell cultures including cardiac myocytes,
  • Applications of the technology for drug discovery using acute and cultured slices.

Examples of studies directed at understanding the origins and functions of various rhythmic activities in neuronal ensembles.


Cognitive Neuroscience Monitor Neuroscience bioengineering cells classification neurons physiology tissue

Editors and affiliations

  • Makoto Taketani
    • 1
  • Michel Baudry
    • 2
  1. 1.Panasonic Research and DevelopmentCompany of AmericaCypressUSA
  2. 2.Department of Biological SciencesUniversity of Southern California, Los AngelesLos AngelesUSA

Bibliographic information

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