© 2006

Managing Failed Anti-Reflux Therapy

  • Mark K. Ferguson
  • M. Brian Fennerty


  • Definitive text on Gastroesophageal Reflux Disease (GERD), outlining pathophysiology and medical management


Table of contents

  1. Front Matter
    Pages i-x
  2. Peter J. Kahrilas, John E. Pandolfino
    Pages 1-13
  3. Federico Cuenca-Abente, Brant K. Oelschlager, Carlos A. Pellegrini
    Pages 57-65
  4. Gianmattia del Genio, Jean-Marie Collard
    Pages 67-77
  5. John G. Hunter, M. Brian Fennerty
    Pages 79-89
  6. Carrie A. Sims, David W. Rattner
    Pages 91-102
  7. Jennefer A. Kieran, Myriam J. Curet
    Pages 127-138
  8. Jose M. Clavero, Philippe Topart, Claude Deschamps
    Pages 139-149
  9. Éric Fréchette, André Duranceau
    Pages 151-162
  10. Steven R. DeMeester
    Pages 175-180
  11. M. Brian Fennerty, Mark K. Ferguson
    Pages 181-185
  12. Back Matter
    Pages 187-196

About this book


Gastroesophageal reflux disease (GERD) affects millions of people in western society. Since the introduction of laparoscopic techniques in the 1990s, it is now one of the most common indications for surgery.

This multiauthored text provides information on the pathophysiology of GERD, appropriate medical management, and proper indications for and performance of surgical and endoscopic procedures for GERD. Thousands of patients will experience inadequate relief from medical therapy or will develop complications from their procedures or recurrent or new symptoms afterwards; this text describes in detail the proper evaluation and management of such patients.

Beginning with an overview of the current understanding of the pathophysiology of GERD, the book moves onto new information regarding tissue susceptibility, the role of bile and digestive enzymes, and cyclic changes in LES tone. The next chapters are devoted to standard therapeutic options for GERD, including lifestyle changes, pharmacologic therapy, and surgery. In addition, newer endoscopic treatments, such as Stretta, Endocinch, injection of bulking agents, as well as others, are described. Subsequent chapters focus on the causes for failure of medical, endoscopic, and surgical therapies. The remainder of the text is a detailed examination of medical, endoscopic, and surgical remedies for these treatment failures.

This text is essential to any physician who manages patients with GERD, including internists, gastroenterologists, general surgeons, and thoracic surgeons.


Antireflux Therapy Gastroesophageal Reflux Disease (GERD) Surgery cancer endoscopy gastroenterology

Editors and affiliations

  • Mark K. Ferguson
    • 1
  • M. Brian Fennerty
    • 2
  1. 1.Professor of Surgery, Head, Thoracic Surgery Service, Department of SurgeryUniversity of ChicagoChicago, ILUSA
  2. 2.Professor of Medicine, Division of Gastroenterology, Department of MedicineOregon Health & Science UniversityPortland, ORUSA

Bibliographic information

  • Book Title Managing Failed Anti-Reflux Therapy
  • Editors Mark K. Ferguson
    M. Brian Fennerty
  • DOI
  • Copyright Information Springer-Verlag London Limited 2006
  • Publisher Name Springer, London
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-1-85233-909-8
  • Softcover ISBN 978-1-84996-956-7
  • eBook ISBN 978-1-84628-011-5
  • Edition Number 1
  • Number of Pages X, 196
  • Number of Illustrations 67 b/w illustrations, 9 illustrations in colour
  • Topics Gastroenterology
    General Surgery
    Thoracic Surgery
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology


From the reviews of the first edition:

"An outstanding review of an increasingly common clinical problem, namely, the management of field antireflux therapy. The selection of chapter authors is outstanding, the combinations of topics presented are well thought out and the layout and presentation are excellent. Clinicians who see patients on any form of GERD therapy will find the book insightful, scholarly and useful."

J.H. Peters, MD, FACS, Diseases of the Esophagus

"This is a multi-authored textbook edited by a surgeon and a gastroenterologist. … The content and references are up-to-date. The quality of the drawings, black and white and colour illustrations is generally excellent throughout the book. … This is a useful and comprehensive textbook for surgeons who want to manage such complex patients and understand the importance of a truly multidisciplinary approach." (L. Bonavina, Digestive and Liver Disease, Issue 38, 2006)