Managing Failed Anti-Reflux Therapy

  • Mark K. Ferguson
  • M. Brian Fennerty

Table of contents

  1. Front Matter
    Pages i-x
  2. Peter J. Kahrilas, John E. Pandolfino
    Pages 1-13
  3. Federico Cuenca-Abente, Brant K. Oelschlager, Carlos A. Pellegrini
    Pages 57-65
  4. Gianmattia del Genio, Jean-Marie Collard
    Pages 67-77
  5. John G. Hunter, M. Brian Fennerty
    Pages 79-89
  6. Carrie A. Sims, David W. Rattner
    Pages 91-102
  7. Jennefer A. Kieran, Myriam J. Curet
    Pages 127-138
  8. Jose M. Clavero, Philippe Topart, Claude Deschamps
    Pages 139-149
  9. Éric Fréchette, André Duranceau
    Pages 151-162
  10. Steven R. DeMeester
    Pages 175-180
  11. M. Brian Fennerty, Mark K. Ferguson
    Pages 181-185
  12. Back Matter
    Pages 187-196

About this book


Gastroesophageal reflux disease (GERD) affects millions of people in western society. Since the introduction of laparoscopic techniques in the 1990s, it is now one of the most common indications for surgery.

This multiauthored text provides information on the pathophysiology of GERD, appropriate medical management, and proper indications for and performance of surgical and endoscopic procedures for GERD. Thousands of patients will experience inadequate relief from medical therapy or will develop complications from their procedures or recurrent or new symptoms afterwards; this text describes in detail the proper evaluation and management of such patients.

Beginning with an overview of the current understanding of the pathophysiology of GERD, the book moves onto new information regarding tissue susceptibility, the role of bile and digestive enzymes, and cyclic changes in LES tone. The next chapters are devoted to standard therapeutic options for GERD, including lifestyle changes, pharmacologic therapy, and surgery. In addition, newer endoscopic treatments, such as Stretta, Endocinch, injection of bulking agents, as well as others, are described. Subsequent chapters focus on the causes for failure of medical, endoscopic, and surgical therapies. The remainder of the text is a detailed examination of medical, endoscopic, and surgical remedies for these treatment failures.

This text is essential to any physician who manages patients with GERD, including internists, gastroenterologists, general surgeons, and thoracic surgeons.


Antireflux Therapy Gastroesophageal Reflux Disease (GERD) Surgery cancer endoscopy gastroenterology

Editors and affiliations

  • Mark K. Ferguson
    • 1
  • M. Brian Fennerty
    • 2
  1. 1.Professor of Surgery, Head, Thoracic Surgery Service, Department of SurgeryUniversity of ChicagoChicago, ILUSA
  2. 2.Professor of Medicine, Division of Gastroenterology, Department of MedicineOregon Health & Science UniversityPortland, ORUSA

Bibliographic information

Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology