Mathematical Methods for Protein Structure Analysis and Design

C.I.M.E. Summer School, Martina Franca, Italy, July 9-15, 2000. Advanced Lectures

  • Concettina Guerra
  • Sorin Istrail
Conference proceedings

Part of the Lecture Notes in Computer Science book series (LNCS, volume 2666)

Also part of the Lecture Notes in Bioinformatics book sub series (LNBI, volume 2666)

Table of contents

  1. Front Matter
  2. Giuseppe Lancia, Sorin Istrail
    Pages 1-33
  3. Carlo Ferrari, Concettina Guerra
    Pages 57-82
  4. Mary Ellen Bock, Concettina Guerra
    Pages 83-97
  5. Maricel Kann, Richard A. Goldstein
    Pages 99-108
  6. Dean C. Adams, Gavin J. P. Naylor
    Pages 109-115
  7. Claus Lundegaard, Thomas Nordahl Petersen, Morten Nielsen, Henrik Bohr, Jacob Bohr, Søren Brunak et al.
    Pages 117-122
  8. Andrea Rossi, Cristian Micheletti, Flavio Seno, Amos Maritan
    Pages 123-129
  9. John R. Quine, Timothy A. Cross
    Pages 131-137
  10. Flavio Seno, Cristian Micheletti, Amos Maritan, Jayanth R. Banavar
    Pages 139-145
  11. Yves-Henri Sanejouand, Georges Trinquier
    Pages 147-153
  12. Back Matter

About these proceedings


The papers collected in this volume reproduce contributions by leading sch- arstoaninternationalschoolandworkshopwhichwasorganizedandheldwith thegoaloftakinga snapshotofadiscipline undertumultuous growth. Indeed, the area of protein folding, docking and alignment is developing in response to needs for a mix of heterogeneous expertise spanning biology, chemistry, mathematics, computer science, and statistics, among others. Some of the problems encountered in this area are not only important for the scienti?c challenges they pose, but also for the opportunities they disclose intermsofmedicalandindustrialexploitation. Atypicalexampleiso?eredby protein-drug interaction (docking), a problem posing daunting computational problems at the crossroads of geometry, physics and chemistry, and, at the same time, a problem with unimaginable implications for the pharmacopoeia of the future. The schoolfocused on problems posed by the study of the mechanisms - hind protein folding, and explored di?erent ways of attacking these problems under objective evaluations of the methods. Together with a relatively small core of consolidated knowledge and tools, important re?ections were brought to this e?ort by studies in a multitude of directions and approaches. It is obviously impossible to predict which, if any, among these techniques will prove completely successful, but it is precisely the implicit dialectic among them that best conveys the current ?avor of the ?eld. Such unique diversity and richness inspired the format of the meeting, and also explains the slight departure of the present volume from the typical format in this series: the exposition of the current sediment is complemented here by a selection of quali?ed specialized contributions.


algorithms calculus computational biology computational molecular biology data analysis genome neural learning pattern analysis pattern matching protein design protein informatics protein structure analysis statistical learning structural similarity structure prediction

Editors and affiliations

  • Concettina Guerra
    • 1
  • Sorin Istrail
    • 2
  1. 1.Topic Chairs 
  2. 2.Center for Molecular Biology and Computer Sciecne DepartmentBrown UniversityUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2003
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-40104-9
  • Online ISBN 978-3-540-44827-3
  • Series Print ISSN 0302-9743
  • Series Online ISSN 1611-3349
  • Buy this book on publisher's site
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