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Genomics and Proteomics

Functional and Computational Aspects

  • Sándor Suhai

Table of contents

  1. Front Matter
    Pages i-viii
  2. Jörg D. Hoheisel
    Pages 1-3
  3. Michael Bittner, Yidong Chen, Sally A. Amundson, Javed Khan, Albert J. Fornace Jr., Edward R. Dougherty et al.
    Pages 5-25
  4. Nicolas Pollet, Volker Gawantka, Hajo Delius, Christof Niehrs
    Pages 27-35
  5. Daniel L. Hartl, E. Fidelma Boyd, Carlos D. Bustamante, Stanley A. Sawyer
    Pages 37-49
  6. B. Chevreux, T. Pfisterer, S. Suhai
    Pages 51-65
  7. William R. Taylor, Nigel P. Brown
    Pages 67-82
  8. Jens Reich, David Brett, Jens Hanke
    Pages 83-94
  9. Roderic Guigó, Moisés Burset, Pankaj Agarwal, Josep F. Abril, Randall F. Smith, James W. Fickett
    Pages 95-106
  10. Joachim Klose
    Pages 107-120
  11. Jorg Langowski, Carsten Mehring, Markus Hammermann, Konstantin Klenin, Christian Munkel, Katalin Tóth et al.
    Pages 121-132
  12. H. Bornfleth, C. Cremer, T. Cremera, S. Dietzel, P. Edelmann, R. Eils et al.
    Pages 133-140
  13. Jerome Baudry, Serge Crouzy, Benoit Roux, Jeremy C. Smith
    Pages 141-148
  14. E. Rao, G. A. Rappold
    Pages 149-155
  15. Udo Heinemann, Juergen Frevert, Klaus-Peter Hofman, Gerd Illing, Hartmut Oschkinat, Wolfram Saenger et al.
    Pages 179-189
  16. Florence Horn, Mustapha Mokrane, Johnathon Weare, Gerrit Vrien
    Pages 191-214
  17. M. Senger, P. Ernst, K. -H. Glatting
    Pages 215-229
  18. Charles J. Epstein
    Pages 231-242
  19. Back Matter
    Pages 243-250

About this book

Introduction

Genome research will certainly be one of the most important and exciting sci- tific disciplines of the 21st century. Deciphering the structure of the human genome, as well as that of several model organisms, is the key to our understanding how genes fu- tion in health and disease. With the combined development of innovativetools, resources, scientific know-how, and an overall functional genomic strategy, the origins of human and other organisms’geneticdiseases can be traced. Scientificresearch groups and dev- opmental departments of several major pharmaceutical and biotechnological companies are using new, innovative strategies to unravel how genes function, elucidating the gene protein product, understanding how genes interact with others-both in health and in the disease state. Presently, the impact of the applications of genome research on our society in medicine, agriculture and nutrition will be comparable only to that of communication technologies. In fact, computational methods, including networking, have been playing a substantial role even in genomics and proteomics from the beginning. We can observe, however, a fundamental change of the paradigm in life sciences these days: research focused until now mostly on the study of single processes related to a few genes or gene products, but due to technical developments of the last years we can now potentially identify and analyze all genes and gene products of an organism and clarify their role in the network of lifeprocesses.

Keywords

Chromosom DNA Microarray Proteomics bioinformatics cell nucleus gene expression genetics proteins

Editors and affiliations

  • Sándor Suhai
    • 1
  1. 1.Deutsches KrebsforschungszentrumHeidelbergGermany

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