© 1994

Topics in Fluorescence Spectroscopy

Probe Design and Chemical Sensing

  • Joseph R. Lakowicz

Part of the Topics in Fluorescence Spectroscopy book series (TIFS, volume 4)

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Richard B. Thompson
    Pages 151-181
  3. Guillermo A. Casay, Dana B. Shealy, Gabor Patonay
    Pages 183-222
  4. Henryk Szmacinski, Joseph R. Lakowicz
    Pages 295-334
  5. K. T. V. Grattan, Z. Y. Zhang
    Pages 335-376
  6. David J. S. Birch, Graham Hungerford
    Pages 377-416
  7. Govind Rao, Shabbir B. Bambot, Simon C. W. Kwong, Henryk Szmacinski, Jeffrey Sipior, Raja Holavanahali et al.
    Pages 417-448
  8. Alvydas J. Ozinskas
    Pages 449-496
  9. Back Matter
    Pages 497-501

About this book


Time-resolved fluorescence spectroscopy is widely used as a research tool in bioch- istry and biophysics. These uses of fluorescence have resulted in extensive knowledge of the structure and dynamics of biological macromolecules. This information has been gained by studies of phenomena that affect the excited state, such as the local environment, quenching processes, and energy transfer. Topics in Fluorescence Spectroscopy, Volume 4: Probe Design and Chemical Sensing reflects a new trend, which is the use of time-resolved fluorescence in analytical and clinical chemistry. These emerging applications of time-resolved fluorescence are the result of continued advances in laser detector and computer technology. For instance, pho- multiplier tubes (PMT) were previously bulky devices. Miniature PMTs are now available, and the performance of simpler detectors is continually improving. There is also considerable effort to develop fluorophores that can be excited with the red/ne- infrared (NIR) output of laser diodes. Using such probes, one can readily imagine small time-resolved fluorometers, even hand-held devices, being used fordoctor’s office or home health care.


biomedical applications chemistry clinical chemistry fluorescence fluorescence spectroscopy luminescence metals reactions sensors spectroscopy tissue transition metal

Editors and affiliations

  • Joseph R. Lakowicz
    • 1
  1. 1.Center for Fluorescence Spectroscopy and Department of Biological ChemistryUniversity of Maryland School of MedicineBaltimoreUSA

About the editors

Dr. J.R. Lakowicz is Professor of Biochemistry at the University of Maryland School of Medicine and Director of the Center for Fluorescence Spectroscopy. Dr. Lakowicz has published over 400 scientific articles, has edited numerous books, holds 16 issued patents, and is the sole author of the widely used text, Principles of Fluorescence Spectroscopy, also published by Kluwer Academic/Plenum Publishers, now in its Second Edition.

Bibliographic information

  • Book Title Topics in Fluorescence Spectroscopy
  • Book Subtitle Probe Design and Chemical Sensing
  • Editors Joseph R. Lakowicz
  • Series Title Topics in Fluorescence Spectroscopy
  • DOI
  • Copyright Information Kluwer Academic Publishers 1994
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-0-306-44784-6
  • Softcover ISBN 978-1-4757-8808-2
  • eBook ISBN 978-0-306-47060-8
  • Edition Number 1
  • Number of Pages XVIII, 502
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Biochemistry, general
    Analytical Chemistry
  • Buy this book on publisher's site
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From reviews of previous volumes:

`The [editor] has mastered a commendable task; the topics appear to be well covered, and the volumes will enhance the collection of the fluorescence spectroscopist.'
Applied Spectroscopy

`Indispensable for researchers in the life sciences, should also be consulted by analytical chemists.'
Trends in Analytical Chemistry