Taurine 4

Taurine and Excitable Tissues

  • Laura Della Corte
  • Ryan J. Huxtable
  • Giampietro Sgaragli
  • Keith F. Tipton

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 483)

Table of contents

  1. Front Matter
    Pages i-xxiv
  2. Keynote Presentation

  3. Appreciations

  4. Plenary Presentations

    1. Jang-Yen Wu, Weiqing Chen, Xiao Wen Tang, Hong Jin, Todd Foos, John V. Schloss et al.
      Pages 35-44
    2. Annamaria De Luca, Sabata Pierno, Domenico Tricarico, Jean-François Desaphy, Antonella Liantonio, Mariagrazia Barbieri et al.
      Pages 45-56
    3. Stephen Schaffer, Viktoriya Solodushko, Junichi Azuma
      Pages 57-69
  5. Basic Aspects and Peripheral Actions of Taurine

    1. Deborah L. Bella, Young-Hye Kwon, Lawrence L. Hirschberger, Martha H. Stipanuk
      Pages 71-85
    2. Mitri Palmi, Gisele Tchuisseu Youmbi, Giampietro Sgaragli, Antonella Meini, Alberto Benocci, Fabio Fusi et al.
      Pages 87-96
    3. Xiaobin Han, Andrea M. Budreau, Russell W. Chesney
      Pages 97-108
    4. Kyoko Takahashi, Yuko Ohyabu, Stephen W. Schaffer, Junichi Azuma
      Pages 109-116
    5. S.I. Baskin, T.L. Barnhouse, K.T. Filipiak, J.C. Bloom, M.J. Novak
      Pages 117-126
    6. Ha Won Kim, Eun Jin Lee, Won Bae Kim, Byong KakKim
      Pages 127-135
  6. Metabolic and Nutritional Aspects

    1. E. Kibayashi, H. Yokogoshi, H. Mizue, K. Miura, K. Yoshita, H. Nakagawa et al.
      Pages 137-142
    2. Giuseppina Pitari, Silvestro Duprè, Anna Maria Ragnelli, Pierpaolo Aimola, Camillo Di Giulio, Fernanda Amicarelli
      Pages 149-156
    3. Giuseppina Pitari, Silvestro Duprè, Alessandra Spirito, Giovanni Antonini, Fernanda Amicarelli
      Pages 157-162
    4. Laura Pecci, Gabriella Montefoschi, Mario Fontana, Silvestro Duprè, Mara Costa, Doriano Cavallini
      Pages 163-168
    5. Shigeru Murakami, Yukiko Kondo, Takatoshi Nagate
      Pages 177-186

About this book

Introduction

Mitochondria from mammalian tissues possess an elaborate system for 2+ 2+ transporting Ca across their inner membrane which consists of Ca import, 2+ via the Ca uniporter, in response to the mitochondrial membrane 2+ + potential ?? and of Ca release by an antiport system in exchange for H + 9,23 or Na (see Fig. l) . Because the uniporter is dependent upon the external 2+ 2+ 2+ 2+ Ca concentration ([Ca ]), mitochondria accumulate Ca until the [Ca ] o o 2+ decreases to the level at which the uniporter activity balances the Ca efflux. 2+ The [Ca ] at which the uniporter and efflux activities are equal is defined o the “setpoint” andcorresponds to values between 0.3-3µM. 2+ Figure 1. The Ca transport system of the inner membrane of mammalian mitochondria. U, + 2+ + + uniporter. I, Na -independent efflux mechanism or Ca /2H exchanger. D, Na -dependent 2+ + efflux mechanism or Ca /2Na exchanger. PTP, permeability transition pore. FP, 11 flavoprotein. ?? membrane potential. ? pH gradient. Adapted from .

Keywords

Lipid Nutrition Oxidation RNA cells enzymes ethanol gene expression metabolism neurons thermoregulation tissue transcription

Editors and affiliations

  • Laura Della Corte
    • 1
  • Ryan J. Huxtable
    • 2
  • Giampietro Sgaragli
    • 3
  • Keith F. Tipton
    • 4
  1. 1.University of FlorenceFlorenceItaly
  2. 2.University of Arizona College of MedicineTucson
  3. 3.University of SienaSienaItaly
  4. 4.Trinity CollegeDublinIreland

Bibliographic information

  • DOI https://doi.org/10.1007/b112581
  • Copyright Information Kluwer Academic Publishers 2002
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-0-306-46447-8
  • Online ISBN 978-0-306-46838-4
  • Series Print ISSN 0065-2598
  • About this book
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