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Chromogranins

Functional and Clinical Aspects

  • Book
  • © 2002

Overview

Editors:
  1. Karen B. Helle

    1. University of Bergen, Bergen, Norway

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    You can also search for this editor in PubMed   Google Scholar

  2. Dominique Aunis

    1. INSERM U338, Centre of Neurochemistry, Strasbourg, France

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 482)

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Table of contents (32 chapters)

  1. Functional Aspects of Biologically Active Sequences

    1. Pancreastatin

      • Victor Sánchez-Margalet, Carmen González-Yanes, José Santos-Alvarez, Souad Najib
      Pages 247-262

    2. The Novel Catecholamine Release-Inhibitory Peptide Catestatin (Chromogranin A344–364)

      • Sushil K. Mahata, Manjula Mahata, Carolyn V. Livsey Taylor, Laurent Taupenot, Robert J. Parmer, Daniel T. O’Connor
      Pages 263-277

    3. Secretoneurin — A Novel Link Between The Nervous and the Immune System

      • Christian M. Kähler, Reiner Fischer-Colbrie
      Pages 279-290

    4. Chromogranin A Induces a Neurotoxic Phenotype in Brain Microglial Cells

      • Jaroslava Ciesielski-Treska, Dominique Aunis
      Pages 291-298

    5. Antibacterial and Antifungal Peptides Derived from Chromogranins and Proenkephalin-A

      • Marie-Hélène Metz-Boutigue, Karine Lugardon, Yannick Goumon, Roselyne Raffner, Jean-Marc Strub, Dominique Aunis
      Pages 299-315

  2. Clinical Aspects of the Circulating Prohormones

    1. Measurements of Chromogranins and Chromogranin-Related Peptides by Immunological Methods

      • Mats Stridsberg
      Pages 319-327

    2. Chromogranins as Diagnostic and Prognostic Markers in Neuroendocrine Tumours

      • Kjell Oberg, Mats Stridsberg
      Pages 329-337

    3. Assessment of Chromogranin a Using Two-Site Immunoassay

      • François Degorce
      Pages 339-350

    4. Chromogranin A and Tumor Necrosis Factor-α (TNF) in Chronic Heart Failure

      • Angelo Corti, Roberto Ferrari, Claudio Ceconi
      Pages 351-359

    5. Chromogranin A (CGA) and the Enterochromaffin-Like (ECL) Cell

      • Helge L. Waldum, Unni Syversen
      Pages 361-367

    6. Chromogranins in Non-Endocrine Tumours

      • Noriko Kimura
      Pages 369-373

  3. Concluding Remarks

    1. Chromogranin A in Human Disease

      • Daniel T. O’Connor, Sushil K. Mahata, Laurent Taupenot, Manjula Mahata, Carolyn V. Livsey Taylor, Mala T. Kailasam et al.
      Pages 377-388

    2. A Physiological Role for the Granins as Prohormones for Homeostatically Important Regulatory Peptides?

      • Karen B. Helle, Dominique Aunis
      Pages 389-397

  4. Back Matter

    Pages 399-405
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Keywords

About this book

Proceedings of Session VII of the Tenth International Symposium on Chromaffin Cell Biology, held August 25-28, 1999, in Bergen, Norway, and a post-symposium workshop on Chromogranins: from Fundamental Physiology to Clinical Aspects, held August 28, 1999, on board the coastal steamer MS Richard With.
This book deals with the chromogranins, secretory prohormones from the diffuse neuroendocrine system. The current concepts of their structure, biogenesis, biosynthesis, secretion, tissue-specific distribution, and processing are presented for the first time all within one volume, with emphasis on the functional aspects of the biologically active sequences and the clinical perspectives of the circulation prohormones.

Reviews

`I recommend Chromogranins for students and basic scientists interested not only in chromogranins but also in peptide processing and secretory granule proteins.'
Trends in Endocrinology and Metabolism, 13:6 (2002)

Editors and Affiliations

  • University of Bergen, Bergen, Norway

    Karen B. Helle

  • INSERM U338, Centre of Neurochemistry, Strasbourg, France

    Dominique Aunis

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