Proteases In The Brain

  • Uwe Lendeckel
  • Nigel M. Hooper

Part of the Proteases In Biology and Disease book series (PBAD, volume 3)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Stephen J. Crocker, Patrice D. Smith, David S. Park
    Pages 25-61
  3. Susan M. Knoblach, Alan I. Faden
    Pages 79-108
  4. Bernd C. Kieseier, Fabian Bernal
    Pages 109-137
  5. Stefan Brocke, Andreas Steinbrecher, Aliza Bitonl, Maya Ratner, Vera Preller, Bettina Rotthauwe et al.
    Pages 139-150
  6. Sajani S. Lakka, Jasti S. Rao
    Pages 151-177
  7. M. Antonieta Valenzuela, Luis Cartier, Aron D. Mosnaim, Marion E. Wolf, Ana María Kettlun, Lucía Collados et al.
    Pages 179-202
  8. Mathias Hallberg, Pierre Le Grevès, Fred Nyberg
    Pages 203-234
  9. John W. Wright, Joseph W. Harding
    Pages 235-270
  10. Nobuko Mataga, Takao K. Hensch
    Pages 271-301
  11. Hiroshi Nakanishi
    Pages 303-322
  12. Corey C. Ford, Gary A. Rosenberg
    Pages 351-371
  13. Back Matter
    Pages 373-383

About this book


In all organs of the body proteases have critical roles to play both in normal development and functioning and in disease states. The brain is no exception to this, with proteases having emerging roles in synaptic plasticity, memory, neurodegenerative disorders such as Alzheimer’s, Parkinson’s and prion diseases, ischemia and traumatic brain injury, inflammatory and infectious diseases, and tumour progression. Proteases in the Brain brings together a wide range of topics under this central theme and highlights the large number of proteases involved in these normal and disease processes.

Proteases in the Brain reviews the role and regulation of proteases in

Alzheimer’s disease

brain ischemia and traumatic brain injury

human glioma

inflammatory and infectious diseases of the central nervous system

metabolism of the prion protein

modulating synaptic activity

multiple sclerosis

neuronal plasticity and memory consolidation

Parkinson’s disease

processing, conversion and inactivation of neuropeptides.

Proteases in the Brain is a timely and useful source of information both for those well versed in the role of proteases in the brain and for those who are beginning to realize the important role of this family of enzymes in brain function and dysfunction.


Alzheimer Nervous System Parkinson enzymes metabolism neuropeptides

Editors and affiliations

  • Uwe Lendeckel
    • 1
  • Nigel M. Hooper
    • 2
  1. 1.Otto-von-Guericke UniversityMagdeburgGermany
  2. 2.University of LeedsLeedsUK

Bibliographic information

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