Basic and Clinical Advances

  • Kazunori Sango
  • Junji Yamauchi
  • Toru Ogata
  • Keiichiro Susuki

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1190)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Myelination in Neural Development and Regeneration

    1. Front Matter
      Pages 1-1
    2. Tomohiro Torii, Yuki Miyamoto, Junji Yamauchi
      Pages 3-22
    3. Daisuke Kato, Hiroaki Wake
      Pages 43-51
    4. Chikako Hayashi, Nobuharu Suzuki
      Pages 53-62
  3. Specialized Structures Along the Myelinated Nerve Fibers

    1. Front Matter
      Pages 63-63
    2. Leonid M. Yermakov, Lulu A. Hong, Domenica E. Drouet, Ryan B. Griggs, Keiichiro Susuki
      Pages 65-83
    3. Yang Sui, Huy Bang Nguyen, Truc Quynh Thai, Kazuhiro Ikenaka, Nobuhiko Ohno
      Pages 145-163
    4. Hiroko Baba, Tomoko Ishibashi
      Pages 165-179
    5. Nobuo Terada, Yurika Saitoh, Akio Kamijo, Junji Yamauchi, Nobuhiko Ohno, Takeharu Sakamoto
      Pages 181-198
  4. Myelin Pathology in the Central Nervous System

  5. Myelin Pathology in the Peripheral Nervous System

    1. Front Matter
      Pages 299-299
    2. Tatsufumi Murakami, Yoshihide Sunada
      Pages 301-321
    3. Kenichi Kaida
      Pages 323-331
    4. Satoshi Kuwabara, Sonoko Misawa
      Pages 333-343
    5. Naoko Niimi, Shizuka Takaku, Hideji Yako, Kazunori Sango
      Pages 357-369
    6. Tatsufumi Murakami, Yoshihide Sunada
      Pages 371-378

About this book


This book presents the latest exciting advances in understanding of the structure and function of myelin in the central and peripheral nervous systems under normal and pathological conditions. Readers will find state of the art information from the perspectives of both basic neuroscience and clinical neurology and neuropathology. Detailed attention is paid to the findings and implications of recent research on the myelin-forming glial cells such as oligodendrocytes and Schwann cells. The discussion of myelin pathology encompasses a wide range of diseases and conditions, including, for example, multiple sclerosis, Pelizaeus-Merzbacher disease, traumatic brain and spinal cord injuries, brain tumors of glial cell origin, Charcot-Marie-Tooth disease, immune-mediated neuropathy, and diabetic neuropathy. The authors comprise researchers at the cutting edge of biotechnology and experts in the diseases discussed. The clearly written text is supported by numerous high-quality light and electron microscopy, CT, and MR images.


Schwann cells Node of Ranvier Demyelinating diseases Peripheral neuropathies Oligodendrocytes Myelination Neural development Neural regeneration Myelin pathology

Editors and affiliations

  • Kazunori Sango
    • 1
  • Junji Yamauchi
    • 2
  • Toru Ogata
    • 3
  • Keiichiro Susuki
    • 4
  1. 1.Diabetic Neuropathy Project, Department of Sensory and Motor SystemsTokyo Metropolitan Institute of Medical ScienceTokyoJapan
  2. 2.Laboratory of Molecular Neuroscience and NeurologyTokyo University of Pharmacy and Life ScienceHachiojiJapan
  3. 3.Department of Rehabilitation for the Movement FunctionsResearch Institute, National Rehabilitation CenterTokorozawaJapan
  4. 4.Department of Neuroscience, Cell Biology, and Physiology, Boonshoft School of MedicineWright State UniversityDaytonUSA

Bibliographic information

Industry Sectors
Health & Hospitals