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Mycobacterium Tuberculosis: Molecular Infection Biology, Pathogenesis, Diagnostics and New Interventions

  • Seyed Ehtesham Hasnain
  • Nasreen Z. Ehtesham
  • Sonam Grover
Book

Table of contents

  1. Front Matter
    Pages i-xxii
  2. Pathogenesis and Epidemiology of Tuberculosis

    1. Front Matter
      Pages 1-1
    2. Ashfaq Hasan
      Pages 3-16
    3. Ruxana T. Sadikot
      Pages 27-36
    4. Surendra K. Sharma, Alladi Mohan
      Pages 37-53
  3. Molecular and Infection Biology of M. tuberculosis

    1. Front Matter
      Pages 101-101
    2. Sonam Grover, Rishabh Gangwar, Salma Jamal, Sabeeha Ali, Khairun Nisaa, Nasreen Z. Ehtesham et al.
      Pages 103-122
    3. Ravi Pal, Faiza Nazar, Sangita Mukhopadhyay
      Pages 123-150
    4. Farha Naz, Javeed Ahmad, Mohd Shariq, Mohd Arish, Javaid A. Sheikh, Seyed E. Hasnain et al.
      Pages 151-170
    5. Rajni Garg, Rajesh Mani, Manish Gupta, Deeksha Tripathi, Harish Chandra, Rakesh Bhatnagar et al.
      Pages 189-201
    6. Nooruddin Khan, Gillipsie Minhas, K. Kala jyothi, Jyoti Sharma
      Pages 203-220
    7. Prajna Tripathi, Janendra K. Batra
      Pages 221-240
    8. Tarina Sharma, Sonam Grover, Nasreen Z. Ehtesham, Seyed E. Hasnain
      Pages 241-255
    9. Ashutosh Kumar, Anwar Alam, Pranami Bharadwaj, Sharmistha Tapadar, Mamta Rani, Seyed E. Hasnain
      Pages 257-274
    10. Manoj Thakur, K. Muniyappa
      Pages 275-300
    11. Jaishree Garhyan, Bikul Das, Rakesh Bhatnagar
      Pages 301-314
    12. Anwar Alam, Ashutosh Kumar, Prajna Tripathi, Nasreen Z. Ehtesham, Seyed E. Hasnain
      Pages 315-333
  4. Vaccines, Diagnostics and New Interventions

    1. Front Matter
      Pages 335-335
    2. Ashfaq Hasan, Sai Haranath Praveen, Chandrakant Tarke, Fahad Abdullah
      Pages 355-374
    3. Gurpreet Kaur, Deepjyoti K. Das, Sanpreet Singh, Junaid Khan, Mohammad Sajid, Hilal Bashir et al.
      Pages 375-405
    4. Himanshu Vashistha, K. K. Chopra
      Pages 419-450
    5. Pooja Singh, Jasmine Samal, Sheeba Zarin, Ravikrishnan Elangovan, Seyed E. Hasnain, Nasreen Z. Ehtesham
      Pages 451-461
    6. Garima Khare, Prachi Nangpal, Anil K. Tyagi
      Pages 463-495
    7. Pankaj Kumar, Urvashi B. Singh, Gyanu Lamichhane, Elizabeth Story-Roller
      Pages 497-514

About this book

Introduction

This book reviews recent advances in the molecular and infection biology, pathology, and molecular epidemiology of Mycobacterium tuberculosis, as well as the identification and validation of novel molecular drug targets for the treatment of this mycobacterial disease.

Despite being completely curable, tuberculosis is still one of the leading global causes of death.  M. tuberculosis, the causative organism – one of the smartest pathogens known – adopts highly intelligent strategies for survival and pathogenesis. 

Presenting a wealth of information on the molecular infection biology of M. tuberculosis, as well as nontuberculous mycobacteria (NTM), the book provides an overview of the functional role of the PE/PPE group of proteins, which is exclusive to the genus Mycobacteria, of host-pathogen interactions, and virulence. It also explores the pathogenesis of the infection, pathology, epidemiology, and diagnosis of NTM. Finally it discusses current and novel approaches in vaccine development against tuberculosis, including the role of nanotechnology. 

With state-of-the-art contributions from experts in the respective domains, this book is an informative resource for practitioners as well as medical postgraduate students and researchers.

Keywords

Mycobacterium tuberculosis Virulence and pathogenesis Mesenchymal stem cells Host pathogen interactions Nontuberculous mycobacteria

Editors and affiliations

  • Seyed Ehtesham Hasnain
    • 1
  • Nasreen Z. Ehtesham
    • 2
  • Sonam Grover
    • 3
  1. 1.JH Institute of Molecular Medicine, Jamia HamdardNew DelhiIndia
  2. 2.Inflammation Biology and Cell Signaling LaboratoryICMR-National Institute of Pathology, Safdarjung Hospital CampusNew DelhiIndia
  3. 3.JH Institute of Molecular Medicine, Jamia HamdardNew DelhiIndia

Bibliographic information

Industry Sectors
Biomedicine
Pharma
Biotechnology