Epigenetics in Allergy and Autoimmunity

  • Christopher Chang
  • Qianjin Lu

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1253)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. Lian Zhang, Qianjin Lu, Christopher Chang
      Pages 3-55
    3. Angela Ceribelli, Carlo Selmi
      Pages 95-104
  3. Allergic Diseases

    1. Front Matter
      Pages 105-105
    2. Christopher Chang, Haijing Wu, Qianjin Lu
      Pages 141-152
    3. Andrew Long, Bryan Bunning, Vanitha Sampath, Rosemarie H. DeKruyff, Kari C. Nadeau
      Pages 153-181
  4. Autoimmune Diseases

    1. Front Matter
      Pages 183-183
    2. Haijing Wu, Christopher Chang, Qianjin Lu
      Pages 185-207
    3. Shuai Shao, Johann E. Gudjonsson
      Pages 209-221
    4. Zhiguo Xie, Christopher Chang, Gan Huang, Zhiguang Zhou
      Pages 223-257
    5. Yikang Li, Ruqi Tang, Xiong Ma
      Pages 259-283
    6. Anne Bordron, Valérie Devauchelle-Pensec, Christelle Le Dantec, Arthur Capdeville, Wesley H. Brooks, Yves Renaudineau
      Pages 285-308
    7. Vera Sau-Fong Chan
      Pages 309-374

About this book


This book will address the growing roles of epigenetics in disease pathogenesis, and review the contribution of epigenetic modifications to disease onset and progression. The roles that epigenetics plays in facilitating effects of the environment on allergy and immunologic diseases will be reviewed. The book is divided into three parts – the first is an introduction to epigenetics and the methods that have been developed to study epigenetics, the second addresses epigenetics in allergic diseases and the third part will cover epigenetics in autoimmune diseases. With the rapid expansion of knowledge of how genes are regulated and how this regulation affects disease phenotypes, this book will be attractive to experienced researchers as well as those just launching an epigenetics research program. It will also be of interest to allergist, immunologists, rheumatologists and dermatologist who are engaged in clinical practice as a resource for understanding the basis for personalized and precision medicine. For example, the role that epigenetics plays in the pathogenesis in various allergic and autoimmune disorders and how this determines disease phenotypes will be covered extensively in this book. This book will thus help fill the gap in available resources on epigenetics in allergy and autoimmune diseases.


Epigenetics Allergy Autoimmunity Genetics DNA methylation Histone modification microRNA

Editors and affiliations

  • Christopher Chang
    • 1
  • Qianjin Lu
    • 2
  1. 1.Division of Pediatric Immunology and AllergyJoe DiMaggio Children’s HospitalHollywoodUSA
  2. 2.Department of Dermatology, Hunan Key Laboratory of Medical EpigenomicsSecond Xiangya Hospital, Central South UniversityChangshaChina

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Singapore Pte Ltd. 2020
  • Publisher Name Springer, Singapore
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-981-15-3448-5
  • Online ISBN 978-981-15-3449-2
  • Series Print ISSN 0065-2598
  • Series Online ISSN 2214-8019
  • Buy this book on publisher's site
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