Health Impacts of Developmental Exposure to Environmental Chemicals

  • Reiko Kishi
  • Philippe Grandjean

Table of contents

  1. Front Matter
    Pages i-xi
  2. Introduction

  3. Adverse Health Effects on Human Developing Organs Caused by Environmental Chemicals-the Role That Chemicals Might Play

    1. Front Matter
      Pages 23-23
    2. Machiko Minatoya, Tomoyuki Hanaoka, Reiko Kishi
      Pages 25-53
    3. Tomoyuki Hanaoka, Chihiro Miyashita, Kumiko Itoh, Reiko Kishi
      Pages 55-68
    4. Takahiko Mitsui, Fumihiro Sata, Reiko Kishi
      Pages 69-99
    5. Atsuko Araki, Tina Kold Jensen
      Pages 101-129
    6. Sachiko Itoh
      Pages 131-152
    7. Carsten Heilmann, Philippe Grandjean
      Pages 175-190
  4. Impact of Environmental Chemical Hazards on Human Development

    1. Front Matter
      Pages 221-221
    2. Ching-Chung Lin, Meng-Shan Tsai, Mei-Huei Chen, Pau-Chung Chen
      Pages 247-277
    3. Kyungho Choi, Sunmi Kim
      Pages 359-373
    4. Hui-Ju Wen, Han-Bin Huang, Tsung-Lin Tsai, Shu-Li Wang
      Pages 375-404
    5. Mei-Lien Chen, Chia-Huang Chang, Machiko Minatoya
      Pages 405-437
  5. Important Aspects of Research for Prevention and Strategy

    1. Front Matter
      Pages 439-439
    2. Léa Maitre, Martine Vrijheid
      Pages 463-484
    3. Fumihiro Sata, Sumitaka Kobayashi, Reiko Kishi
      Pages 485-512
    4. Wilfried Karmaus, Ali H. Ziyab, Nandini Mukherjee
      Pages 513-529
    5. Philippe Grandjean
      Pages 531-542
  6. Closing

    1. Front Matter
      Pages 543-543

About this book


This book provides concise and cutting-edge studies on threats resulting from exposure to environmental chemicals that can affect human health and development, with a particular emphasis on the DOHaD concept. The book is divided into five main parts, the first of which includes an introduction to theimpacts of developmental exposure to environmental chemicals and historical perspectives, while the second focuses on how environmental chemicals can affect human organs, including neurodevelopment, immune functions, etc. In turn, the third part addresses the characteristics of specific chemicals and their effects on human health and development, while the fourth part provides a basis for future studies by highlighting the latest innovations in toxicology, remaining challenges, and promising strategies in children’s environmental health research, as well as ideas on how to bridge the gap between research evidence and practical policymaking. The fifth and last part outlines further research directions and related policymaking aspects.

Health Impacts of Developmental Exposure to Environmental Chemicals will appeal to young and veteran researchers, students, and physicians (especially gynecologists and pediatricians) who are seeking comprehensive information on how children’s health can be affected by harmful chemicals and other environmental toxicants.


Congenital Heart Malformation Birth Defect Low Birth Weight ADHD ASD Environmental Chemical Hazards PM 2.5 Hazardous Material DOHaD Environmental Toxicant

Editors and affiliations

  • Reiko Kishi
    • 1
  • Philippe Grandjean
    • 2
  1. 1.Center for Environmental and Health SciencesHokkaido UniversitySapporoJapan
  2. 2.Department of Environmental Health Harvard T.H. Chan School of Public HealthBostonUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Singapore Pte Ltd. 2020
  • Publisher Name Springer, Singapore
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-981-15-0519-5
  • Online ISBN 978-981-15-0520-1
  • Series Print ISSN 2364-8333
  • Series Online ISSN 2364-8341
  • Buy this book on publisher's site
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