Neuroglia in Neurodegenerative Diseases

  • Alexei Verkhratsky
  • Margaret S. Ho
  • Robert Zorec
  • Vladimir Parpura

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1175)

Table of contents

  1. Front Matter
    Pages i-x
  2. Alexei Verkhratsky, Margaret S. Ho, Robert Zorec, Vladimir Parpura
    Pages 1-13
  3. Alexei Verkhratsky, Margaret S. Ho, Vladimir Parpura
    Pages 15-44
  4. Alexei Verkhratsky, Vladimir Parpura, Nina Vardjan, Robert Zorec
    Pages 45-91
  5. Nina Vardjan, Vladimir Parpura, Alexei Verkhratsky, Robert Zorec
    Pages 93-115
  6. Arthur M. Butt, Maria Papanikolaou, Andrea Rivera
    Pages 117-128
  7. Tuan Leng Tay, Micaël Carrier, Marie-Ève Tremblay
    Pages 129-148
  8. Alexei Verkhratsky, Margaret S. Ho, Nina Vardjan, Robert Zorec, Vladimir Parpura
    Pages 149-179
  9. Alexei Verkhratsky, Robert Zorec, Jose Julio Rodriguez-Arellano, Vladimir Parpura
    Pages 181-197
  10. M. S. Jorge, Marianna Bugiani
    Pages 199-225
  11. Chiara F. Valori, Giulia Guidotti, Liliana Brambilla, Daniela Rossi
    Pages 227-272
  12. Alexei Verkhratsky, Vladimir Parpura, Jose Julio Rodriguez-Arellano, Robert Zorec
    Pages 273-324
  13. Arthur M. Butt, Irene Chacon De La Rocha, Andrea Rivera
    Pages 325-333
  14. Margaret S. Ho
    Pages 335-353
  15. Michelle Gray
    Pages 355-381

About this book


This book provides a comprehensive overview of the role of neuroglia in neurodegenerative diseases. Neuroglia are the most abundant cells in the nervous system and consist of several distinct cell types, such as astrocytes, oligodendrocytes,and microglia. Accumulating evidence suggests that neuroglia participate in the neurodegenerative process, and as such are essential players in a variety of diseases, including Alzheimer’s, Parkinson’s, and Huntington’s.

Intended for researchers and students, the book presents recent advances concerning the biology of neuroglia as well as their interaction with neurons during disease progression. In addition, to highlight the function of neuroglia in different types of neurodegenerative disease, it also discusses their mechanisms and effects on protecting or damaging neurons.


Neuroglia Neurodegeneration Alzheimer's Disease a-synucleinopathies Neuropathology

Editors and affiliations

  • Alexei Verkhratsky
    • 1
  • Margaret S. Ho
    • 2
  • Robert Zorec
    • 3
  • Vladimir Parpura
    • 4
  1. 1.Faculty of Biology, Medicine and HealthThe University of ManchesterManchesterUK
  2. 2.School of Life Science and TechnologyShanghaiTech UniversityShanghaiChina
  3. 3.Institute of PathophysiologyUniversity of LjubljanaLjubljanaSlovenia
  4. 4.Department of NeurobiologyThe University of Alabama at BirminghamBirminghamUSA

Bibliographic information

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