© 2019

Protein Structure and Modeling

  • Maximizes reader insights into the most recent advancements in understanding the structure of proteins

  • Incorporates a wealth of the most recent experimental and theoretical research in the field

  • Includes an introduction into methods of protein structure determination, design, and modeling


Table of contents

  1. Front Matter
    Pages i-viii
  2. Natalya Kurochkina
    Pages 1-52
  3. Natalya Kurochkina
    Pages 53-62
  4. Natalya Kurochkina
    Pages 63-89
  5. Natalya Kurochkina
    Pages 91-109
  6. Natalya Kurochkina
    Pages 111-151
  7. Natalya Kurochkina
    Pages 153-183
  8. Natalya Kurochkina
    Pages 185-191
  9. Natalya Kurochkina
    Pages 193-209
  10. Back Matter
    Pages 211-276

About this book


The volume covers the advances made by the most recent experimental and theoretical research in the structure of the most extensively studied main biological macromolecules - the proteins. Proteins are remarkably regular highly ordered biopolymers. Their precise organization allows living organisms to reliably perform complex functions.

The book features an introduction into methods of protein structure determination, design, and modeling, and addresses the structural principles of fibrous and globular proteins such as enzymes, channels, signaling molecules and adaptors, and the relationships between primary, secondary, tertiary, and quaternary structure. The main focus is on determinants of protein conformation, canonical and noncanonical amino acids and polypeptides, conformational states and transitions, structure elements and arrangements, protein folds, helical assemblies, multiprotein complexes, structure and function relationships, the specificity of molecular recognition, ligand binding, and involvement in cellular processes. 

The book is a must read for scientists, engineers, teachers, undergraduate and graduate students, business professionals, and curious learners in the fields of Life Sciences and Biomedical Research.

Prof. Natalya Kurochkina heads The School of Theoretical Modeling, Washington, DC, USA, teaches, and conducts research. She has PhD in Biophysics, from the Institute of Protein Research, Russian Academy of Sciences and worked as a postdoctoral fellow at the National Cancer Institute of the National Institute of Health. Her research focuses on principles of protein structure and protein conformation, and determinants of specificity of molecular recognition


Protein Structure Allosteric Regulation Structure Determination Protein Modeling Conformational dynamics

Authors and affiliations

  1. 1.Department of BiophysicsSchool of Theoretical ModelingWashington, DCUSA

Bibliographic information

  • Book Title Protein Structure and Modeling
  • Authors Natalya Kurochkina
  • DOI
  • Copyright Information Springer Nature Singapore Pte Ltd. 2019
  • Publisher Name Springer, Singapore
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-981-13-6600-0
  • Softcover ISBN 978-981-13-6603-1
  • eBook ISBN 978-981-13-6601-7
  • Edition Number 1
  • Number of Pages VIII, 276
  • Number of Illustrations 21 b/w illustrations, 60 illustrations in colour
  • Topics Protein Science
  • Buy this book on publisher's site
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