Hearing Loss: Mechanisms, Prevention and Cure

  • Huawei Li
  • Renjie Chai

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1130)

Table of contents

  1. Front Matter
    Pages i-v
  2. Yan Chen, Shasha Zhang, Renjie Chai, Huawei Li
    Pages 1-16
  3. Jin Guo, Renjie Chai, Huawei Li, Shan Sun
    Pages 17-36
  4. Zu-hong He, Ming Li, Sheng-yu Zou, Fu-ling Liao, Yan-yan Ding, Hong-guo Su et al.
    Pages 59-71
  5. Tao Yang, Luo Guo, Longhao Wang, Xiaoyu Yu
    Pages 73-92
  6. Wenwen Liu, Xue Wang, Man Wang, Haibo Wang
    Pages 93-107
  7. Dongmei Tang, Huawei Li, Lin Chen
    Pages 109-128
  8. Fei Chen, Wenli Ni, Wenyan Li, Huawei Li
    Pages 129-144
  9. Ling Lu, Xiaoli Zhang, Xia Gao
    Pages 145-163
  10. Yang Qiu, Jianhua Qiu
    Pages 165-180

About this book


This book systematically discusses the pathogenesis, prevention, and the current and potential clinical treatment of hearing loss, as well as the latest advances in hearing research. Hearing loss is a prevalent sensory disorder, which according to a 2015 World Health Organization (WHO) report affected 9% of the global population in 2015. As populations continue to age, more and more people are suffering from the condition, with 60% of those aged between 65 and 75 affected. Hearing loss seriously affects patients’ ability to work ability and quality of life, and as such deafness has become an increasingly urgent social problem around the globe. Sensorineural hearing loss is mainly caused by damage to the hair cells (HCs), and the subsequent loss of spiral ganglion neurons (SGNs). Damage to the HCs in the inner ear can result from exposure to loud noises and environmental and chemical toxins as well as genetic disorders, aging, and certain medications. This book provides ENT specialists and researchers, as well as individuals affected a comprehensive introduction to the field of hearing loss.


hearing loss hair cell spiral ganglion neuron regeneration gene therapy

Editors and affiliations

  • Huawei Li
    • 1
  • Renjie Chai
    • 2
  1. 1.Key Laboratory of Hearing Medicine of NHFPC, ENT Institute and Otorhinolaryngology Department, Shanghai Engineering Research Centre of Cochlear Implant, Affiliated Eye and ENT Hospital, State Key Laboratory of Medical NeurobiologyFudan UniversityShanghaiChina
  2. 2.MOE Key Laboratory for Developmental Genes and Human Disease, Institute of Life Sciences, Jiangsu Province High-Tech Key Laboratory for Bio-Medical ResearchSoutheast UniversityNanjingChina

Bibliographic information

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