Health Technology Assessment in Japan

Policy, Pharmacoeconomic Methods and Guidelines, Value, and Beyond

  • Isao Kamae

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Isao Kamae
    Pages 1-24
  3. Isao Kamae
    Pages 25-62
  4. Isao Kamae
    Pages 107-115
  5. Isao Kamae
    Pages 117-160
  6. Isao Kamae
    Pages 161-204
  7. Isao Kamae
    Pages 205-228
  8. Back Matter
    Pages 229-269

About this book


Representing the first book on the topic, this work offers the reader an introduction to the Japanese systems for health technology assessment (HTA) officially introduced by the Ministry of Health, Labour and Welfare (MHLW) in 2016. Policy and guidelines are discussed, with the relevant methods and conditions of cost-effectiveness analysis explained alongside. Numerous instructive examples and exercises, ranging from basic to advanced, impart valuable knowledge and insight on the quantitative methods for economic evaluation, which will appeal to both beginners and experts.

This guidebook is authored by Japan’s foremost expert in HTA and pharmacoeconomics, with a view to strengthening the reader’s expertise in value-based healthcare and decision-making. The methods presented are essential to informing regulatory, local and patient decisions; as such, the book is equally recommended to industry and government, as well as academia, and anyone with an interest in Japanese HTA.


Pharmacoeconomics Cost-effectiveness Economic evaluation Value in healthcare Value-based pricing Universal health coverage Appraisal ICER Acceptability curve QALY Acceptability frontier Efficiency frontier EVPI Meta-analysis Propensity score Bayes Budget impact Japanese-style premium Markov model

Authors and affiliations

  • Isao Kamae
    • 1
  1. 1.Graduate School of Public PolicyThe University of TokyoTokyoJapan

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Singapore Pte Ltd. 2019
  • Publisher Name Adis, Singapore
  • eBook Packages Medicine
  • Print ISBN 978-981-13-5792-3
  • Online ISBN 978-981-13-5793-0
  • Buy this book on publisher's site
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Chemical Manufacturing
Finance, Business & Banking