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© 2019

Molecular Toxicology in Caenorhabditis elegans

Benefits

  • Provides a systematic understanding the knowledge system of molecular toxicology in C. elegans

  • Thoroughly examines the principles of molecular signalling pathways regulating the toxicity of toxicants or stresses in C. elegans

  • With ample color figures

Book

Table of contents

  1. Front Matter
    Pages i-xviii

About this book

Introduction

This book will focus on the molecular basis of oxidative stress induced by toxicants or stresses and various molecular signalling pathways in regulating the toxicity of toxicants or stresses in Caenorhabditis elegans. It will also cover the discussion on the aspects of response signals, G-protein coupled receptors and ion channels, specific molecular signals, and epigenetic signals involved in the regulation of toxicity from toxicants or stresses. The molecular basis for adaptive response for transgenerational toxicity of environmental toxicants or stresses will be further discussed. Nematode Caenorhabditis elegans is a classic model animal with well-described genetic and developmental backgrounds based on the study of life science, and has been further successfully and widely used in both toxicity assessment and toxicological study of various environmental toxicants or stresses. Based on related available data, this book aims at providing a systematic understanding of the knowledge system of molecular toxicology in C. elegans.

Keywords

Molecular toxicology Caenorhabditis elegans Environmental toxicants Signalling pathways Oxidative stress

Authors and affiliations

  1. 1.School of MedicineSoutheast UniversityNanjingChina

About the authors

Dr. Dayong Wang is a professor at the Medical School, Southeast University, China. He obtained his Ph.D. from Peking University in 2001 and completed his post-doctoral training at the University of Toronto from 2002 to 2004. His research focuses on toxicology and pathology using Caenorhabditis elegans as a model animal, fields in which he has published more than 160 research articles.

Bibliographic information

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