© 2019

Gastrointestinal Stromal Tumor

Research and Practice

  • Yukinori Kurokawa
  • Yoshito Komatsu

Table of contents

  1. Front Matter
    Pages i-ix
  2. Takahiro Higashi
    Pages 1-9
  3. Hidetaka Yamamoto
    Pages 11-30
  4. Tsuyoshi Takahashi
    Pages 31-48
  5. Tomohiro Yoneyama, Bae Hyeyeol, Yoshio Kitazume, Mitsuhiro Kishino, Ukihide Tateishi
    Pages 49-59
  6. Hirotoshi Kikuchi, Hiroyuki Konno, Hiroya Takeuchi
    Pages 61-77
  7. Muranaka Tetsuhito, Yoshito Komatsu
    Pages 79-87
  8. Souya Nunobe
    Pages 89-107
  9. Yusuke Onozawa
    Pages 109-115
  10. Masato Ozaka
    Pages 117-127
  11. Haruhiko Cho
    Pages 129-144
  12. Yoichi Naito, Toshihiko Doi
    Pages 145-156

About this book


This book provides a comprehensive and up-to-date overview of gastrointestinal stromal tumors (GISTs).

GISTs represent the most common mesenchymal neoplasms arising within the gastrointestinal tract. The causative gene of this disease was originally discovered in Japan by Prof. Seichi Hirota in 1998, and since then numerous important advances – from basic to clinical aspects – have been reported from Japan. Professionals involved in the management of GISTs inevitably cite significant evidence and the state-of-the-art treatments from the Asian region, where has there is and inherently high prevalence of gastrointestinal cancers.

Each expert author elucidates the cutting-edge knowledge on pathophysiology, diagnosis, and treatment of GISTs, especially focusing on the highly valuable data from Japan. This attractive collection benefits not only oncologists but also basic researchers, general physicians and surgeons, as well as paramedical staff and medical students who are dealing with GISTs.


Gastrointestinal cancer Gastrointestinal tract Mesenchymal neoplasm Imatinib Malignancy

Editors and affiliations

  • Yukinori Kurokawa
    • 1
  • Yoshito Komatsu
    • 2
  1. 1.Department of Gastroenterological SurgeryOsaka University Graduate School of MedicineOsakaJapan
  2. 2.Department of Cancer ChemotherapyHokkaido University Hospital Cancer CenterSapporoJapan

About the editors

Dr. Yukinori Kurokawa,

Assistant Professor,

Department of Gastoenterological Surgery,

Graduate School of Medicine,

Osaka University

Dr. Yoshito Komatsu,

Associate Professor,

Department of Cancer Chemotherapy,

Hokkaido University Hospital Cancer Center

Bibliographic information

  • Book Title Gastrointestinal Stromal Tumor
  • Book Subtitle Research and Practice
  • Editors Yukinori Kurokawa
    Yoshito Komatsu
  • DOI
  • Copyright Information Springer Nature Singapore Pte Ltd. 2019
  • Publisher Name Springer, Singapore
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-981-13-3205-0
  • eBook ISBN 978-981-13-3206-7
  • Edition Number 1
  • Number of Pages IX, 156
  • Number of Illustrations 12 b/w illustrations, 39 illustrations in colour
  • Topics Surgical Oncology
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Oncology & Hematology
Surgery & Anesthesiology


“The audience includes students, researchers, residents, oncologists, and surgeons. ... It includes the current knowledge regarding demographics and characteristics of at‐risk groups, the newest evaluation of individual tumors with helpful color photographs of tumor slides, and detailed descriptions of different aspects of tumor genetics, with illustrations of signal mapping and mutations. … This is as comprehensive a book on GIST as I can imagine, and it fills knowledge gaps for clinicians caring for these patients.” (Ryan Lehmann, Doody's Book Reviews, June 21, 2019)​