© 2019

Premalignant Conditions of the Oral Cavity

  • Peter A. Brennan
  • Tom Aldridge
  • Raghav C. Dwivedi

Part of the Head and Neck Cancer Clinics book series (HNCC)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Peter A. Brennan, Tom Aldridge
    Pages 1-6
  3. Carolina Cavalieri Gomes, Marina Gonçalves Diniz, Ricardo Santiago Gomez
    Pages 7-26
  4. Camile S. Farah, Kate Shearston, Amanda Phoon Nguyen, Omar Kujan
    Pages 27-66
  5. Rajiv S. Desai, Ravikant S. Ganga, Raghav C. Dwivedi
    Pages 67-85
  6. Lakshminarasimman Parasuraman, Munita Bal, Prathamesh S. Pai
    Pages 87-95
  7. Felipe Paiva Fonseca, Peter A. Brennan, Ricardo Santiago Gomez, Hélder Antônio Rebelo Pontes, Eduardo Rodrigues Fregnani, Márcio Ajudarte Lopes et al.
    Pages 97-117
  8. Martina K. Shephard, Esther A. Hullah
    Pages 119-158
  9. Divya Mehrotra
    Pages 159-184
  10. Ben Tudor-Green
    Pages 209-227
  11. Camile S. Farah, Katherine Pollaers, Agnieszka Frydrych
    Pages 229-276

About this book


Oral squamous cell carcinoma (SCC) is the 13th commonest cancer worldwide, and the most common cancer in the Asian subcontinent due to the widespread habit of tobacco and betel nut chewing. Despite many advances in diagnosis and treatment, the survival statistics have only marginally improved. However our understanding of the disease process and transformation from pre-cancerous lesions of the oral mucosa to an invasive SCC cancer and their progression has expanded exponentially.

There are many conditions of the oral mucosa that can progress to an invasive malignancy.  A thorough understanding of these conditions is a prerequisite for all those involved in the management of the diseases of the oral mucosa and head and neck region.

The recognition and timely treatment of potentially pre-malignant conditions of the oral cavity can minimize the change to an overt malignancy in many patients through patient education, appropriate treatment and surveillance.

In this book we cover relevant anatomy, biology, diagnosis and latest management strategies for pre-cancerous conditions that affect the oral mucosa. The respective chapters are written by expert contributors from around the world, lending the book a global perspective and making it an essential guide for all those involved in the management of pre-malignant lesions arising in this challenging anatomical region.


Oral pathology Cancer Pathogenesis Prevention Management

Editors and affiliations

  • Peter A. Brennan
    • 1
  • Tom Aldridge
    • 2
  • Raghav C. Dwivedi
    • 3
  1. 1.Department of Oral and Maxillofacial SurgeryQueen Alexandra HospitalPortsmouthUK
  2. 2.Department of Oral and Maxillofacial SurgeryQueen Alexandra HospitalPortsmouthUK
  3. 3.Department of Otolaryngology, Head Neck SurgeryQueen Elizabeth University HospitalGlasgowUK

About the editors

Peter Brennan MD, FRCS (Eng), FRCSI, Hon FRCS (Glasgow), FDS RCS (Eng) 

Professor Peter Brennan is a Consultant Oral and Maxillofacial Surgeon at the Queen Alexandra Hospital, Portsmouth, UK with an interest in head and neck oncology and reconstruction. He has a personal chair in surgery in recognition of his research and education profile, publishing over 530 papers to date as well as editing 5 major textbooks (including lead editor of the 2 volume Maxillofacial Surgery) used successfully worldwide. He is lead editor for the new Gray’s Surgical Anatomy - sister to the famous Gray’s Anatomy itself.

Peter is committed to teaching and education at all levels and was previous Honorary Editor of the British Journal of Oral and Maxillofacial Surgery. In addition to reviewing for many reputed journals, he is the current editor of the Journal of Oral Pathology and Medicine- one of the most well respected journals in this specialty area. Peter has research interests in oral cancer, neck anatomy, patient safety and human factors.

Tom Aldridge, BDS MFDS BM FRCS

Tom Aldridge is an Oral and Maxillofacial Consultant in Queen Alexandra Hospital, Portsmouth, UK. He received his Bachelor of Dental Surgery from the University of Bristol in 2000 and Bachelor of Medicine from Southampton University in 2008. He completed basic surgical training and specialist training in Oral and Maxillofacial training in 2015.

Tom specialises in facial trauma, orthognathic surgery, skin surgery and dentoalveolar surgery and has a keen in Medical Education and Training

He has published widely across the specialty and presented nationally and internationally.


Raghav Dwivedi, DOHNS, MS (ENT), FRCS (Glasg), PhD (Lond), FRCS (ORL-HNS)

Raghav Dwivedi is a Consultant Head Neck Surgeon at the Queen Elizabeth University Hospital, Glasgow. He completed ENT and head neck surgery specialty training from the UK and India. He also completed head neck research fellowship at the Royal Marsden Hospital and the Institute of Cancer Research London and head neck surgical fellowships at Nottingham University Hospital, Cambridge University Hospitals, Portsmouth University Hospitals, and Imperial College, London. He holds an intercollegiate FRCS (ORL-HNS) from the Royal College of Surgeons of England, PhD from the Institute of Cancer Research, University of London, UK and MS (ENT) from the King George’s Medical University, India.

He is a dedicated Head neck and ENT surgeon, and has a unique blend of high quality clinical and research experience. His areas of interest are minimally invasive head neck, thyroid and parathyroid surgery, HPV related head neck cancers and outcome research. To date he has published 80 scientific papers in peer-reviewed indexed journals, 21 chapters (including one in upcoming edition of Scott-Brown’s Otolaryngology: Head and Neck Surgery) and edited one head neck Surgery book. He has also served on the editorial board of 6 specialty journals and has been scientific reviewer for 35 peer-reviewed indexed journals including BMJ, Cancer, Head Neck, Oral oncology, Surgical.

Bibliographic information

  • Book Title Premalignant Conditions of the Oral Cavity
  • Editors Peter A. Brennan
    Tom Aldridge
    Raghav C. Dwivedi
  • Series Title Head and Neck Cancer Clinics
  • Series Abbreviated Title Head and Neck Cancer Clinics
  • DOI
  • Copyright Information Peter A. Brennan, Tom Aldridge, Raghav C. Dwivedi, Rehan Kazi 2019
  • Publisher Name Springer, Singapore
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-981-13-2930-2
  • eBook ISBN 978-981-13-2931-9
  • Series ISSN 2364-4060
  • Series E-ISSN 2364-4079
  • Edition Number 1
  • Number of Pages XIV, 276
  • Number of Illustrations 3 b/w illustrations, 48 illustrations in colour
  • Topics Oncology
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Oncology & Hematology