Advances in Asthma

Pathophysiology, Diagnosis and Treatment

  • Akihito Yokoyama

Table of contents

  1. Front Matter
    Pages i-viii
  2. Pathophysiology

    1. Front Matter
      Pages 1-1
    2. Tohru Sakamoto, Nobuyuki Hizawa
      Pages 3-14
    3. Koichiro Asano
      Pages 15-25
    4. Koichi Takagi, Kentaro Machida, Hiromasa Inoue
      Pages 27-39
    5. Arihiko Kanehiro
      Pages 41-52
    6. Koichi Fukunaga
      Pages 53-61
  3. Diagnosis

    1. Front Matter
      Pages 63-63
    2. Satoshi Konno
      Pages 65-70
    3. Kenji Izuhara, Satoshi Nunomura, Junya Ono, Masayuki Takai, Yasuhiro Nanri
      Pages 71-81
    4. Masami Taniguchi, Chihiro Mitsui, Hiroaki Hayashi
      Pages 101-113
  4. Treatment

    1. Front Matter
      Pages 115-115
    2. Tomohiro Ichikawa, Hisatoshi Sugiura
      Pages 117-131
    3. Takashi Iwanaga, Akiko Sano, Osamu Nishiyama, Hiroyuki Sano, Yuji Tohda
      Pages 157-165
    4. Yasuhiro Gon, Mari Hikichi, Shu Hashimoto
      Pages 167-175
    5. Hiroshi Ohnishi, Akihito Yokoyama
      Pages 177-189

About this book


This book provides discussions on bronchial asthma from a clinical perspective, focusing on the recent studies on its pathophysiology, diagnosis and treatment. It also explores the lastest findings regarding the phenotypes and endotypes of asthmatic patients, making it of particular interest to those involved with non-eosinophilic asthma and eosinophilic asthma. Further, it discusses the importance of ILC 2 in eosinophilic asthma, and the accumulated results from the forced oscilliation technique and periostin that are actively practiced in Japan. As some aspects of diagnosis and treatment are different in Western and Asian countries, it is important that the data is disseminated around the globe. 

The clinical questions addressed by the authors are critical and thought provoking, while the questions raised by the editors are instructive, informative and provide new perspectives on unresolved issues. This book appeals to wide readership from beginning learners to physicians in clinical practice and scholars engaging in basic research. 


IL-33 T Helper Cell Th2 cell Corticosteroid-Resistance Forced Oscilliation Technique FOT Fractional Exhaled Nitric Oxcide FeNO Anti-IgE IgE Bronchial Thermoplasty COPD Eosinophic Asthma Non-eosinophic Asthma ILC2

Editors and affiliations

  • Akihito Yokoyama
    • 1
  1. 1.Department of Hematology and Respiratory MedicineKochi Medical SchoolNankoku-shiJapan

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Singapore Pte Ltd. 2019
  • Publisher Name Springer, Singapore
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-981-13-2789-6
  • Online ISBN 978-981-13-2790-2
  • Series Print ISSN 2509-5552
  • Series Online ISSN 2509-5560
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology