Implication of Quorum Sensing System in Biofilm Formation and Virulence

  • Pallaval Veera Bramhachari

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Introduction to Microbial Quorum Sensing

    1. Front Matter
      Pages 1-1
    2. G. Mohana Sheela, A. M. V. N. Prathyusha, Nageswara Rao Reddy Neelapu, Pallaval Veera Bramhachari
      Pages 7-16
    3. Laura Fernandez-García, Lucia Blasco, Rocío Trastoy, Rodolfo García-Contreras, Thomas K. Wood, Maria Tomás
      Pages 17-27
    4. Jin Zhou, Zhong-hua Cai
      Pages 29-46
  3. Functional Aspects of Quorum Sensing in Microbes

    1. Front Matter
      Pages 47-47
    2. Pallaval Veera Bramhachari, N. M. Yugandhar, A. M. V. N. Prathyusha, G. Mohana Sheela, Jalaja Naravula, Nagam Venkateswarlu
      Pages 49-66
    3. Abhik Saha, Kriti Arora, Andaleeb Sajid, Gunjan Arora
      Pages 81-109
    4. Parasuraman Paramanantham, Subhaswaraj Pattnaik, Siddhardha Busi
      Pages 111-132
    5. Rajinikanth Mohan, Marie Benton, Emily Dangelmaier, Zhengqing Fu, Akila Chandra Sekhar
      Pages 133-160
    6. Humera Quadriya, S. Adeeb Mujtaba Ali, J. Parameshwar, M. Manasa, M. Yahya Khan, Bee Hameeda
      Pages 161-177
  4. Quorum Sensing Regulated Behaviors in Fungi

    1. Front Matter
      Pages 193-193
    2. Prerna Pathak, Parul Sahu
      Pages 195-204
  5. Quorum Sensing Regulated Behaviours in Gram- Negative Bacteria

  6. QS-Regulated Behaviours in Gram- Positive Bacteria

    1. Front Matter
      Pages 295-295
    2. Devanabanda Mallaiah, Pallaval Veera Bramhachari
      Pages 329-335
  7. Other Related Topics on Quorum Sensing

    1. Front Matter
      Pages 349-349
    2. Sarangam Majumdar, Sisir Roy
      Pages 351-368
    3. Surekha Challa, G. Mohana Sheela, Nageswara Rao Reddy Neelapu
      Pages 369-381

About this book


This book illustrates the importance and significance of Quorum sensing (QS), it’s critical roles in regulating diverse cellular functions in microbes, including bioluminescence, virulence, pathogenesis, gene expression, biofilm formation and antibiotic resistance. Microbes can coordinate population behavior with small molecules called autoinducers (AHL) which serves as a signal of cellular population density, triggering new patterns of gene expression for mounting virulence and pathogenesis. Therefore, these microbes have the competence to coordinate and regulate explicit sets of genes by sensing and communicating amongst themselves utilizing variety of signals. This book descry emphasizes on how bacteria can coordinate an activity and synchronize their response to external signals and regulate gene expression. The chapters of the book provide the recent advancements on various functional aspects of QS systems in different gram positive and gram negative organisms. 

Finally, the book also elucidates a comprehensive yet a representative description of a large number of challenges associated with quorum sensing signal molecules viz. virulence, pathogenesis, antibiotic synthesis, biosurfactants production, persister cells, cell signaling and biofilms, intra and inter-species communications, host-pathogen interactions, social interactions & swarming migration in biofilms.


Quorum sensing Cell-to-cell communication Biofilm Gene expression Autoinducers (AHL)

Editors and affiliations

  • Pallaval Veera Bramhachari
    • 1
  1. 1.Department of BiotechnologyKrishna UniversityMachilipatnamIndia

Bibliographic information

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